The unsynchronized changes of CT image and nucleic acid detection in COVID-19: reports the two cases from Gansu, China

The novel coronavirus disease (COVID-19) outbreak started in December 2019 in Wuhan, China, caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). The CT image is used to assess the disease progress, whereas the continued two times of negative results from SARS-CoV-2 nucleic acid de...

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Bibliographic Details
Published in:Respiratory research 2020-04, Vol.21 (1), p.96-4, Article 96
Main Authors: Gao, Jing, Liu, Jun-Qiang, Wen, Heng-Jun, Liu, Hua, Hu, Wei-Dong, Han, Xia, Li, Chuan-Xing, Wang, Xiao-Jun
Format: Article
Language:English
Subjects:
Adult
Betacoronavirus
Care and treatment
Case studies
CAT scans
China
Clinical Laboratory Techniques
Computed tomography
Coronavirus Infections - diagnosis
Coronavirus Infections - diagnostic imaging
Coronavirus Infections - drug therapy
Coronaviruses
COVID-19
COVID-19 Testing
CT image
Diagnosis
Health services
Humans
Image detection
Letter to the Editor
Lung - diagnostic imaging
Lung - virology
Male
Medical imaging
Medicin och hälsovetenskap
Middle East respiratory syndrome
Nucleic acid detection
Nucleic acids
Pandemics
Pneumonia, Viral - diagnosis
Pneumonia, Viral - diagnostic imaging
Pneumonia, Viral - drug therapy
Respiratory diseases
RNA, Viral - isolation & purification
SARS-CoV-2
Severe acute respiratory syndrome coronavirus 2
Tomography, X-Ray Computed
Viral diseases
Viral Load
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Summary:The novel coronavirus disease (COVID-19) outbreak started in December 2019 in Wuhan, China, caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). The CT image is used to assess the disease progress, whereas the continued two times of negative results from SARS-CoV-2 nucleic acid detection had been considered as a criterion for ending antiviral treatment. We compared the two COVID-19 cases with similar backgrounds and CT image repeated intervals under treatment. Our report highlighted the unsynchronized expression in the changes of CT image and nucleic acid detection in COVID-19, and lasting positive nucleic acid test result in patients recovered from pneumonia. It may be contributed to recognize the disease and improve prevention.
ISSN:1465-993X
1465-9921
1465-993X
1465-9921
DOI:10.1186/s12931-020-01363-7