Impact of severe infections in SLE: an observational study from the Spanish national registry

ObjectiveInfections are a common complication of SLE. Our objective was to evaluate their causes and impact on the survival of patients with SLE.MethodsAnalysis of the admissions and death causes in patients diagnosed with SLE from the Spanish Hospital Discharge Database and the infection-related de...

Full description

Saved in:
Bibliographic Details
Published in:Lupus science & medicine 2022-10, Vol.9 (1), p.e000711
Main Authors: Moreno-Torres, Victor, Martínez-Urbistondo, María, Gutiérrez-Rojas, Angela, Castejón, Raquel, Sánchez, Enrique, Calderón-Parra, Jorge, Durán-del Campo, Pedro, Tutor, Pablo, Mellor-Pita, Susana, Vázquez-Comendador, José, Vargas-Núñez, Juan A, Ruiz-Irastorza, Guillermo
Format: Article
Language:English
Subjects:
Co-Morbidities
epidemiology
glucocorticoids
Infections
Observational studies
Population
systemic lupus erythematosus
Citations: Items that this one cites
Items that cite this one
Online Access:Get full text
Tags: Add Tag
No Tags, Be the first to tag this record!
Description
Summary:ObjectiveInfections are a common complication of SLE. Our objective was to evaluate their causes and impact on the survival of patients with SLE.MethodsAnalysis of the admissions and death causes in patients diagnosed with SLE from the Spanish Hospital Discharge Database and the infection-related deaths of the Spanish population from the National Statistical Institute, between 2016 and 2018.Only infections recorded as the main diagnosis were analysed (severe or clinically relevant infection).ResultsAmong 18 430 admissions in patients with SLE, disease activity was the cause of admission in 19% of all patients and infection in 15%. However, infection was the main cause of death (25%) while SLE activity was responsible for only 6% of deaths (p
ISSN:2053-8790
2053-8790
DOI:10.1136/lupus-2022-000711