Profiles of Staphyloccocus aureus isolated from goat persistent mastitis before and after treatment with enrofloxacin

Staphylococcus aureus is one of the main causative agents of mastitis in small ruminants. Antimicrobial use is the major treatment, but there are many flaws linked to resistance, tolerance or persistence. This study aimed to verify changes in resistance, virulence and clonal profiles of S. aureus is...

Full description

Saved in:
Bibliographic Details
Published in:BMC microbiology 2020-05, Vol.20 (1), p.127-127, Article 127
Main Authors: Lima, Magna Coroa, de Barros, Mariana, Scatamburlo, Thalita Moreira, Polveiro, Richard Costa, de Castro, Laís Karolyne, Guimarães, Samuel Henrique Sales, da Costa, Sanely Lourenço, da Costa, Mateus Matiuzzi, Moreira, Maria Aparecida Scatamburlo
Format: Article
Language:English
Subjects:
Animals
Antiinfectives and antibacterials
Antimicrobial agents
Bacteria
Biotechnology industries
Caprine mastitis
Cell division
Comparative analysis
Efflux
Enrofloxacin
Flaw detection
Gene expression
Genes
Goat's milk
Goats
Gram-positive bacteria
Mammary gland
Mammary glands
Mastitis
Milk
Minimum inhibitory concentration
Oxacillin
Pathogens
Penicillin
Persistence
Plasmids
Small ruminants
Staphylococcal enterotoxin H
Staphylococcal enterotoxin J
Staphylococcus aureus
Staphylococcus infections
Tetracyclines
Virulence
Virulence (Microbiology)
Citations: Items that this one cites
Items that cite this one
Online Access:Get full text
Tags: Add Tag
No Tags, Be the first to tag this record!
Description
Summary:Staphylococcus aureus is one of the main causative agents of mastitis in small ruminants. Antimicrobial use is the major treatment, but there are many flaws linked to resistance, tolerance or persistence. This study aimed to verify changes in resistance, virulence and clonal profiles of S. aureus isolated from persistent mastitis goat milk before and after enrofloxacin treatment. MIC increased to at least one antimicrobial in S. aureus isolates after enrofloxacin treatment compared to before. The most detected resistance genes before and after treatment were tetK, tetM, and blaZ, with more resistance genes detected after enrofloxacin treatment (p 
ISSN:1471-2180
1471-2180
DOI:10.1186/s12866-020-01793-9