Loading…

Profiles of Staphyloccocus aureus isolated from goat persistent mastitis before and after treatment with enrofloxacin

Staphylococcus aureus is one of the main causative agents of mastitis in small ruminants. Antimicrobial use is the major treatment, but there are many flaws linked to resistance, tolerance or persistence. This study aimed to verify changes in resistance, virulence and clonal profiles of S. aureus is...

Full description

Saved in:
Bibliographic Details
Published in:BMC microbiology 2020-05, Vol.20 (1), p.127-127, Article 127
Main Authors: Lima, Magna Coroa, de Barros, Mariana, Scatamburlo, Thalita Moreira, Polveiro, Richard Costa, de Castro, Laís Karolyne, Guimarães, Samuel Henrique Sales, da Costa, Sanely Lourenço, da Costa, Mateus Matiuzzi, Moreira, Maria Aparecida Scatamburlo
Format: Article
Language:English
Subjects:
Citations: Items that this one cites
Items that cite this one
Online Access:Get full text
Tags: Add Tag
No Tags, Be the first to tag this record!
cited_by cdi_FETCH-LOGICAL-c597t-f03b96cd963b5f06f592cc1ad2f0db4169e1d6e914c8c029e7ffd056529eed5f3
cites cdi_FETCH-LOGICAL-c597t-f03b96cd963b5f06f592cc1ad2f0db4169e1d6e914c8c029e7ffd056529eed5f3
container_end_page 127
container_issue 1
container_start_page 127
container_title BMC microbiology
container_volume 20
creator Lima, Magna Coroa
de Barros, Mariana
Scatamburlo, Thalita Moreira
Polveiro, Richard Costa
de Castro, Laís Karolyne
Guimarães, Samuel Henrique Sales
da Costa, Sanely Lourenço
da Costa, Mateus Matiuzzi
Moreira, Maria Aparecida Scatamburlo
description Staphylococcus aureus is one of the main causative agents of mastitis in small ruminants. Antimicrobial use is the major treatment, but there are many flaws linked to resistance, tolerance or persistence. This study aimed to verify changes in resistance, virulence and clonal profiles of S. aureus isolated from persistent mastitis goat milk before and after enrofloxacin treatment. MIC increased to at least one antimicrobial in S. aureus isolates after enrofloxacin treatment compared to before. The most detected resistance genes before and after treatment were tetK, tetM, and blaZ, with more resistance genes detected after enrofloxacin treatment (p 
doi_str_mv 10.1186/s12866-020-01793-9
format article
fullrecord <record><control><sourceid>gale_doaj_</sourceid><recordid>TN_cdi_doaj_primary_oai_doaj_org_article_255d6ebd3cf540d2a0f18842dff02081</recordid><sourceformat>XML</sourceformat><sourcesystem>PC</sourcesystem><galeid>A627354856</galeid><doaj_id>oai_doaj_org_article_255d6ebd3cf540d2a0f18842dff02081</doaj_id><sourcerecordid>A627354856</sourcerecordid><originalsourceid>FETCH-LOGICAL-c597t-f03b96cd963b5f06f592cc1ad2f0db4169e1d6e914c8c029e7ffd056529eed5f3</originalsourceid><addsrcrecordid>eNptkk1v1DAQhiMEoqXwBzggS1zgkGI7tuNckKqKj5UqgSicLcce73qVxIvtlPbf4-2W0iDkw4zsZ97RvJ6qeknwKSFSvEuESiFqTHGNSds1dfeoOiasJTUlEj9-kB9Vz1La4kLJpn1aHTWUMUkYP67mrzE4P0BCwaHLrHebmyEYE8yckJ4jlOBTGHQGi1wMI1oHndEOYvIpw5TRqFP22SfUgwsRkJ4s0i5DRDmCzuOe-eXzBsFUOg3hWhs_Pa-eOD0keHEXT6ofHz98P_9cX3z5tDo_u6gN79pcO9z0nTC2E03PHRaOd9QYoi112PaMiA6IFdARZqTBtIPWOYu54CUFy11zUq0OujbordpFP-p4o4L26vYixLXSMXszgKKcF6neNsZxhi3V2BEpGbXOFYMlKVrvD1q7uR_BmjJY1MNCdPky-Y1ahyvVUsZlQ4vAmzuBGH7OkLIafTIwDHqCMCdFGRa8lbTdo6__QbdhjlOxqlCECcFwi_9Sa10G8JMLpa_Zi6ozQduGM8lFoU7_Q5VjYfQmTLD__mXB20VBYTJc57WeU1Kry29Llh5YE0NKEdy9HwSr_ZKqw5Kq4qG6XVLVlaJXD528L_mzlc1vBuDjOA</addsrcrecordid><sourcetype>Open Website</sourcetype><iscdi>true</iscdi><recordtype>article</recordtype><pqid>2414664070</pqid></control><display><type>article</type><title>Profiles of Staphyloccocus aureus isolated from goat persistent mastitis before and after treatment with enrofloxacin</title><source>Open Access: PubMed Central</source><source>Publicly Available Content Database</source><creator>Lima, Magna Coroa ; de Barros, Mariana ; Scatamburlo, Thalita Moreira ; Polveiro, Richard Costa ; de Castro, Laís Karolyne ; Guimarães, Samuel Henrique Sales ; da Costa, Sanely Lourenço ; da Costa, Mateus Matiuzzi ; Moreira, Maria Aparecida Scatamburlo</creator><creatorcontrib>Lima, Magna Coroa ; de Barros, Mariana ; Scatamburlo, Thalita Moreira ; Polveiro, Richard Costa ; de Castro, Laís Karolyne ; Guimarães, Samuel Henrique Sales ; da Costa, Sanely Lourenço ; da Costa, Mateus Matiuzzi ; Moreira, Maria Aparecida Scatamburlo</creatorcontrib><description>Staphylococcus aureus is one of the main causative agents of mastitis in small ruminants. Antimicrobial use is the major treatment, but there are many flaws linked to resistance, tolerance or persistence. This study aimed to verify changes in resistance, virulence and clonal profiles of S. aureus isolated from persistent mastitis goat milk before and after enrofloxacin treatment. MIC increased to at least one antimicrobial in S. aureus isolates after enrofloxacin treatment compared to before. The most detected resistance genes before and after treatment were tetK, tetM, and blaZ, with more resistance genes detected after enrofloxacin treatment (p &lt; 0.05). Occasional variations in efflux system gene detection were observed before and after treatment. Nine virulence genes (hla, fnbA, fnbB, eta, etb, sea, sec, seh, and sej) were detected at both times, and between these, the hla and eta genes were detected more in isolates after treatment. All isolates of S. aureus belonged to the same sequence type (ST) 133, except for two S. aureus isolates prior to enrofloxacin treatment which were classified as ST5 and the other as a new one, ST4966. Isolates of S. aureus 4, 8, and 100 from before and after treatment had identical pulse types, while others obtained from other animals before and after treatment were classified into distinct pulse types. There were occasional changes in the studied profiles of S. aureus isolated before and after treatment of animals with enrofloxacin, which may have contributed to the permanence of bacteria in the mammary gland, even when using traditional treatment, resulting in persistent mastitis.</description><identifier>ISSN: 1471-2180</identifier><identifier>EISSN: 1471-2180</identifier><identifier>DOI: 10.1186/s12866-020-01793-9</identifier><identifier>PMID: 32448145</identifier><language>eng</language><publisher>England: BioMed Central Ltd</publisher><subject>Animals ; Antiinfectives and antibacterials ; Antimicrobial agents ; Bacteria ; Biotechnology industries ; Caprine mastitis ; Cell division ; Comparative analysis ; Efflux ; Enrofloxacin ; Flaw detection ; Gene expression ; Genes ; Goat's milk ; Goats ; Gram-positive bacteria ; Mammary gland ; Mammary glands ; Mastitis ; Milk ; Minimum inhibitory concentration ; Oxacillin ; Pathogens ; Penicillin ; Persistence ; Plasmids ; Small ruminants ; Staphylococcal enterotoxin H ; Staphylococcal enterotoxin J ; Staphylococcus aureus ; Staphylococcus infections ; Tetracyclines ; Virulence ; Virulence (Microbiology)</subject><ispartof>BMC microbiology, 2020-05, Vol.20 (1), p.127-127, Article 127</ispartof><rights>COPYRIGHT 2020 BioMed Central Ltd.</rights><rights>2020. This work is licensed under http://creativecommons.org/licenses/by/4.0/ (the “License”). Notwithstanding the ProQuest Terms and Conditions, you may use this content in accordance with the terms of the License.</rights><rights>The Author(s) 2020</rights><lds50>peer_reviewed</lds50><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c597t-f03b96cd963b5f06f592cc1ad2f0db4169e1d6e914c8c029e7ffd056529eed5f3</citedby><cites>FETCH-LOGICAL-c597t-f03b96cd963b5f06f592cc1ad2f0db4169e1d6e914c8c029e7ffd056529eed5f3</cites><orcidid>0000-0002-6902-2502</orcidid></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktopdf>$$Uhttps://www.ncbi.nlm.nih.gov/pmc/articles/PMC7245832/pdf/$$EPDF$$P50$$Gpubmedcentral$$Hfree_for_read</linktopdf><linktohtml>$$Uhttps://www.proquest.com/docview/2414664070?pq-origsite=primo$$EHTML$$P50$$Gproquest$$Hfree_for_read</linktohtml><link.rule.ids>230,314,727,780,784,885,25753,27924,27925,37012,37013,44590,53791,53793</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/32448145$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Lima, Magna Coroa</creatorcontrib><creatorcontrib>de Barros, Mariana</creatorcontrib><creatorcontrib>Scatamburlo, Thalita Moreira</creatorcontrib><creatorcontrib>Polveiro, Richard Costa</creatorcontrib><creatorcontrib>de Castro, Laís Karolyne</creatorcontrib><creatorcontrib>Guimarães, Samuel Henrique Sales</creatorcontrib><creatorcontrib>da Costa, Sanely Lourenço</creatorcontrib><creatorcontrib>da Costa, Mateus Matiuzzi</creatorcontrib><creatorcontrib>Moreira, Maria Aparecida Scatamburlo</creatorcontrib><title>Profiles of Staphyloccocus aureus isolated from goat persistent mastitis before and after treatment with enrofloxacin</title><title>BMC microbiology</title><addtitle>BMC Microbiol</addtitle><description>Staphylococcus aureus is one of the main causative agents of mastitis in small ruminants. Antimicrobial use is the major treatment, but there are many flaws linked to resistance, tolerance or persistence. This study aimed to verify changes in resistance, virulence and clonal profiles of S. aureus isolated from persistent mastitis goat milk before and after enrofloxacin treatment. MIC increased to at least one antimicrobial in S. aureus isolates after enrofloxacin treatment compared to before. The most detected resistance genes before and after treatment were tetK, tetM, and blaZ, with more resistance genes detected after enrofloxacin treatment (p &lt; 0.05). Occasional variations in efflux system gene detection were observed before and after treatment. Nine virulence genes (hla, fnbA, fnbB, eta, etb, sea, sec, seh, and sej) were detected at both times, and between these, the hla and eta genes were detected more in isolates after treatment. All isolates of S. aureus belonged to the same sequence type (ST) 133, except for two S. aureus isolates prior to enrofloxacin treatment which were classified as ST5 and the other as a new one, ST4966. Isolates of S. aureus 4, 8, and 100 from before and after treatment had identical pulse types, while others obtained from other animals before and after treatment were classified into distinct pulse types. There were occasional changes in the studied profiles of S. aureus isolated before and after treatment of animals with enrofloxacin, which may have contributed to the permanence of bacteria in the mammary gland, even when using traditional treatment, resulting in persistent mastitis.</description><subject>Animals</subject><subject>Antiinfectives and antibacterials</subject><subject>Antimicrobial agents</subject><subject>Bacteria</subject><subject>Biotechnology industries</subject><subject>Caprine mastitis</subject><subject>Cell division</subject><subject>Comparative analysis</subject><subject>Efflux</subject><subject>Enrofloxacin</subject><subject>Flaw detection</subject><subject>Gene expression</subject><subject>Genes</subject><subject>Goat's milk</subject><subject>Goats</subject><subject>Gram-positive bacteria</subject><subject>Mammary gland</subject><subject>Mammary glands</subject><subject>Mastitis</subject><subject>Milk</subject><subject>Minimum inhibitory concentration</subject><subject>Oxacillin</subject><subject>Pathogens</subject><subject>Penicillin</subject><subject>Persistence</subject><subject>Plasmids</subject><subject>Small ruminants</subject><subject>Staphylococcal enterotoxin H</subject><subject>Staphylococcal enterotoxin J</subject><subject>Staphylococcus aureus</subject><subject>Staphylococcus infections</subject><subject>Tetracyclines</subject><subject>Virulence</subject><subject>Virulence (Microbiology)</subject><issn>1471-2180</issn><issn>1471-2180</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2020</creationdate><recordtype>article</recordtype><sourceid>PIMPY</sourceid><sourceid>DOA</sourceid><recordid>eNptkk1v1DAQhiMEoqXwBzggS1zgkGI7tuNckKqKj5UqgSicLcce73qVxIvtlPbf4-2W0iDkw4zsZ97RvJ6qeknwKSFSvEuESiFqTHGNSds1dfeoOiasJTUlEj9-kB9Vz1La4kLJpn1aHTWUMUkYP67mrzE4P0BCwaHLrHebmyEYE8yckJ4jlOBTGHQGi1wMI1oHndEOYvIpw5TRqFP22SfUgwsRkJ4s0i5DRDmCzuOe-eXzBsFUOg3hWhs_Pa-eOD0keHEXT6ofHz98P_9cX3z5tDo_u6gN79pcO9z0nTC2E03PHRaOd9QYoi112PaMiA6IFdARZqTBtIPWOYu54CUFy11zUq0OujbordpFP-p4o4L26vYixLXSMXszgKKcF6neNsZxhi3V2BEpGbXOFYMlKVrvD1q7uR_BmjJY1MNCdPky-Y1ahyvVUsZlQ4vAmzuBGH7OkLIafTIwDHqCMCdFGRa8lbTdo6__QbdhjlOxqlCECcFwi_9Sa10G8JMLpa_Zi6ozQduGM8lFoU7_Q5VjYfQmTLD__mXB20VBYTJc57WeU1Kry29Llh5YE0NKEdy9HwSr_ZKqw5Kq4qG6XVLVlaJXD528L_mzlc1vBuDjOA</recordid><startdate>20200524</startdate><enddate>20200524</enddate><creator>Lima, Magna Coroa</creator><creator>de Barros, Mariana</creator><creator>Scatamburlo, Thalita Moreira</creator><creator>Polveiro, Richard Costa</creator><creator>de Castro, Laís Karolyne</creator><creator>Guimarães, Samuel Henrique Sales</creator><creator>da Costa, Sanely Lourenço</creator><creator>da Costa, Mateus Matiuzzi</creator><creator>Moreira, Maria Aparecida Scatamburlo</creator><general>BioMed Central Ltd</general><general>BioMed Central</general><general>BMC</general><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>ISR</scope><scope>3V.</scope><scope>7QL</scope><scope>7T7</scope><scope>7U9</scope><scope>7X7</scope><scope>7XB</scope><scope>88E</scope><scope>8FD</scope><scope>8FE</scope><scope>8FH</scope><scope>8FI</scope><scope>8FJ</scope><scope>8FK</scope><scope>ABUWG</scope><scope>AFKRA</scope><scope>AZQEC</scope><scope>BBNVY</scope><scope>BENPR</scope><scope>BHPHI</scope><scope>C1K</scope><scope>CCPQU</scope><scope>DWQXO</scope><scope>FR3</scope><scope>FYUFA</scope><scope>GHDGH</scope><scope>GNUQQ</scope><scope>H94</scope><scope>HCIFZ</scope><scope>K9.</scope><scope>LK8</scope><scope>M0S</scope><scope>M1P</scope><scope>M7N</scope><scope>M7P</scope><scope>P64</scope><scope>PIMPY</scope><scope>PQEST</scope><scope>PQQKQ</scope><scope>PQUKI</scope><scope>PRINS</scope><scope>7X8</scope><scope>5PM</scope><scope>DOA</scope><orcidid>https://orcid.org/0000-0002-6902-2502</orcidid></search><sort><creationdate>20200524</creationdate><title>Profiles of Staphyloccocus aureus isolated from goat persistent mastitis before and after treatment with enrofloxacin</title><author>Lima, Magna Coroa ; de Barros, Mariana ; Scatamburlo, Thalita Moreira ; Polveiro, Richard Costa ; de Castro, Laís Karolyne ; Guimarães, Samuel Henrique Sales ; da Costa, Sanely Lourenço ; da Costa, Mateus Matiuzzi ; Moreira, Maria Aparecida Scatamburlo</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c597t-f03b96cd963b5f06f592cc1ad2f0db4169e1d6e914c8c029e7ffd056529eed5f3</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2020</creationdate><topic>Animals</topic><topic>Antiinfectives and antibacterials</topic><topic>Antimicrobial agents</topic><topic>Bacteria</topic><topic>Biotechnology industries</topic><topic>Caprine mastitis</topic><topic>Cell division</topic><topic>Comparative analysis</topic><topic>Efflux</topic><topic>Enrofloxacin</topic><topic>Flaw detection</topic><topic>Gene expression</topic><topic>Genes</topic><topic>Goat's milk</topic><topic>Goats</topic><topic>Gram-positive bacteria</topic><topic>Mammary gland</topic><topic>Mammary glands</topic><topic>Mastitis</topic><topic>Milk</topic><topic>Minimum inhibitory concentration</topic><topic>Oxacillin</topic><topic>Pathogens</topic><topic>Penicillin</topic><topic>Persistence</topic><topic>Plasmids</topic><topic>Small ruminants</topic><topic>Staphylococcal enterotoxin H</topic><topic>Staphylococcal enterotoxin J</topic><topic>Staphylococcus aureus</topic><topic>Staphylococcus infections</topic><topic>Tetracyclines</topic><topic>Virulence</topic><topic>Virulence (Microbiology)</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Lima, Magna Coroa</creatorcontrib><creatorcontrib>de Barros, Mariana</creatorcontrib><creatorcontrib>Scatamburlo, Thalita Moreira</creatorcontrib><creatorcontrib>Polveiro, Richard Costa</creatorcontrib><creatorcontrib>de Castro, Laís Karolyne</creatorcontrib><creatorcontrib>Guimarães, Samuel Henrique Sales</creatorcontrib><creatorcontrib>da Costa, Sanely Lourenço</creatorcontrib><creatorcontrib>da Costa, Mateus Matiuzzi</creatorcontrib><creatorcontrib>Moreira, Maria Aparecida Scatamburlo</creatorcontrib><collection>PubMed</collection><collection>CrossRef</collection><collection>Gale In Context: Science</collection><collection>ProQuest Central (Corporate)</collection><collection>Bacteriology Abstracts (Microbiology B)</collection><collection>Industrial and Applied Microbiology Abstracts (Microbiology A)</collection><collection>Virology and AIDS Abstracts</collection><collection>Health &amp; Medical Collection (ProQuest Medical &amp; Health Databases)</collection><collection>ProQuest Central (purchase pre-March 2016)</collection><collection>Medical Database (Alumni Edition)</collection><collection>Technology Research Database</collection><collection>ProQuest SciTech Collection</collection><collection>ProQuest Natural Science Collection</collection><collection>Hospital Premium Collection</collection><collection>Hospital Premium Collection (Alumni Edition)</collection><collection>ProQuest Central (Alumni) (purchase pre-March 2016)</collection><collection>ProQuest Central (Alumni)</collection><collection>ProQuest Central</collection><collection>ProQuest Central Essentials</collection><collection>Biological Science Collection</collection><collection>ProQuest Central</collection><collection>Natural Science Collection</collection><collection>Environmental Sciences and Pollution Management</collection><collection>ProQuest One Community College</collection><collection>ProQuest Central</collection><collection>Engineering Research Database</collection><collection>Health Research Premium Collection</collection><collection>Health Research Premium Collection (Alumni)</collection><collection>ProQuest Central Student</collection><collection>AIDS and Cancer Research Abstracts</collection><collection>SciTech Premium Collection</collection><collection>ProQuest Health &amp; Medical Complete (Alumni)</collection><collection>ProQuest Biological Science Collection</collection><collection>Health &amp; Medical Collection (Alumni Edition)</collection><collection>PML(ProQuest Medical Library)</collection><collection>Algology Mycology and Protozoology Abstracts (Microbiology C)</collection><collection>Biological Science Database</collection><collection>Biotechnology and BioEngineering Abstracts</collection><collection>Publicly Available Content Database</collection><collection>ProQuest One Academic Eastern Edition (DO NOT USE)</collection><collection>ProQuest One Academic</collection><collection>ProQuest One Academic UKI Edition</collection><collection>ProQuest Central China</collection><collection>MEDLINE - Academic</collection><collection>PubMed Central (Full Participant titles)</collection><collection>Directory of Open Access Journals</collection><jtitle>BMC microbiology</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Lima, Magna Coroa</au><au>de Barros, Mariana</au><au>Scatamburlo, Thalita Moreira</au><au>Polveiro, Richard Costa</au><au>de Castro, Laís Karolyne</au><au>Guimarães, Samuel Henrique Sales</au><au>da Costa, Sanely Lourenço</au><au>da Costa, Mateus Matiuzzi</au><au>Moreira, Maria Aparecida Scatamburlo</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Profiles of Staphyloccocus aureus isolated from goat persistent mastitis before and after treatment with enrofloxacin</atitle><jtitle>BMC microbiology</jtitle><addtitle>BMC Microbiol</addtitle><date>2020-05-24</date><risdate>2020</risdate><volume>20</volume><issue>1</issue><spage>127</spage><epage>127</epage><pages>127-127</pages><artnum>127</artnum><issn>1471-2180</issn><eissn>1471-2180</eissn><abstract>Staphylococcus aureus is one of the main causative agents of mastitis in small ruminants. Antimicrobial use is the major treatment, but there are many flaws linked to resistance, tolerance or persistence. This study aimed to verify changes in resistance, virulence and clonal profiles of S. aureus isolated from persistent mastitis goat milk before and after enrofloxacin treatment. MIC increased to at least one antimicrobial in S. aureus isolates after enrofloxacin treatment compared to before. The most detected resistance genes before and after treatment were tetK, tetM, and blaZ, with more resistance genes detected after enrofloxacin treatment (p &lt; 0.05). Occasional variations in efflux system gene detection were observed before and after treatment. Nine virulence genes (hla, fnbA, fnbB, eta, etb, sea, sec, seh, and sej) were detected at both times, and between these, the hla and eta genes were detected more in isolates after treatment. All isolates of S. aureus belonged to the same sequence type (ST) 133, except for two S. aureus isolates prior to enrofloxacin treatment which were classified as ST5 and the other as a new one, ST4966. Isolates of S. aureus 4, 8, and 100 from before and after treatment had identical pulse types, while others obtained from other animals before and after treatment were classified into distinct pulse types. There were occasional changes in the studied profiles of S. aureus isolated before and after treatment of animals with enrofloxacin, which may have contributed to the permanence of bacteria in the mammary gland, even when using traditional treatment, resulting in persistent mastitis.</abstract><cop>England</cop><pub>BioMed Central Ltd</pub><pmid>32448145</pmid><doi>10.1186/s12866-020-01793-9</doi><tpages>1</tpages><orcidid>https://orcid.org/0000-0002-6902-2502</orcidid><oa>free_for_read</oa></addata></record>
fulltext fulltext
identifier ISSN: 1471-2180
ispartof BMC microbiology, 2020-05, Vol.20 (1), p.127-127, Article 127
issn 1471-2180
1471-2180
language eng
recordid cdi_doaj_primary_oai_doaj_org_article_255d6ebd3cf540d2a0f18842dff02081
source Open Access: PubMed Central; Publicly Available Content Database
subjects Animals
Antiinfectives and antibacterials
Antimicrobial agents
Bacteria
Biotechnology industries
Caprine mastitis
Cell division
Comparative analysis
Efflux
Enrofloxacin
Flaw detection
Gene expression
Genes
Goat's milk
Goats
Gram-positive bacteria
Mammary gland
Mammary glands
Mastitis
Milk
Minimum inhibitory concentration
Oxacillin
Pathogens
Penicillin
Persistence
Plasmids
Small ruminants
Staphylococcal enterotoxin H
Staphylococcal enterotoxin J
Staphylococcus aureus
Staphylococcus infections
Tetracyclines
Virulence
Virulence (Microbiology)
title Profiles of Staphyloccocus aureus isolated from goat persistent mastitis before and after treatment with enrofloxacin
url http://sfxeu10.hosted.exlibrisgroup.com/loughborough?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&ctx_tim=2024-12-24T13%3A21%3A35IST&url_ver=Z39.88-2004&url_ctx_fmt=infofi/fmt:kev:mtx:ctx&rfr_id=info:sid/primo.exlibrisgroup.com:primo3-Article-gale_doaj_&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.atitle=Profiles%20of%20Staphyloccocus%20aureus%20isolated%20from%20goat%20persistent%20mastitis%20before%20and%20after%20treatment%20with%20enrofloxacin&rft.jtitle=BMC%20microbiology&rft.au=Lima,%20Magna%20Coroa&rft.date=2020-05-24&rft.volume=20&rft.issue=1&rft.spage=127&rft.epage=127&rft.pages=127-127&rft.artnum=127&rft.issn=1471-2180&rft.eissn=1471-2180&rft_id=info:doi/10.1186/s12866-020-01793-9&rft_dat=%3Cgale_doaj_%3EA627354856%3C/gale_doaj_%3E%3Cgrp_id%3Ecdi_FETCH-LOGICAL-c597t-f03b96cd963b5f06f592cc1ad2f0db4169e1d6e914c8c029e7ffd056529eed5f3%3C/grp_id%3E%3Coa%3E%3C/oa%3E%3Curl%3E%3C/url%3E&rft_id=info:oai/&rft_pqid=2414664070&rft_id=info:pmid/32448145&rft_galeid=A627354856&rfr_iscdi=true