Strategies and mechanisms targeting Enterococcus faecalis biofilms associated with endodontic infections: a comprehensive review

is one of the main microorganisms that infects root canals, ranking among the most prevalent microorganisms associated with endodontic treatment failure. Given its pervasive presence in persistent endodontic infections, the successful elimination of is crucial for effective endodontic treatment and...

Full description

Saved in:
Bibliographic Details
Published in:Frontiers in cellular and infection microbiology 2024-07, Vol.14, p.1433313
Main Authors: Yang, Shipeng, Meng, Xiuping, Zhen, Yuqi, Baima, Quzhen, Wang, Yu, Jiang, Xinmiao, Xu, Zhibo
Format: Article
Language:English
Subjects:
Anti-Bacterial Agents - pharmacology
antibiotic resistance
biofilms
Biofilms - drug effects
Biofilms - growth & development
Cellular and Infection Microbiology
Dental Pulp Cavity - microbiology
endodontic infection
Enterococcus faecalis
Enterococcus faecalis - drug effects
Enterococcus faecalis - physiology
Gram-Positive Bacterial Infections - microbiology
Humans
mechanisms
Citations: Items that this one cites
Online Access:Get full text
Tags: Add Tag
No Tags, Be the first to tag this record!
Description
Summary:is one of the main microorganisms that infects root canals, ranking among the most prevalent microorganisms associated with endodontic treatment failure. Given its pervasive presence in persistent endodontic infections, the successful elimination of is crucial for effective endodontic treatment and retreatment. Furthermore, can form biofilms - defense structures that microbes use to fight environmental threats. These biofilms confer resistance against host immune system attacks and antibiotic interventions. Consequently, the presence of biofilms poses a significant challenge in the complete eradication of and its associated disease. In response, numerous scholars have discovered promising outcomes in addressing biofilms within root canals and undertaken endeavors to explore more efficacious approaches in combating these biofilms. This study provides a comprehensive review of strategies and mechanisms for the removal of biofilms.
ISSN:2235-2988
2235-2988
DOI:10.3389/fcimb.2024.1433313