A fatal case of early prosthetic valve endocarditis caused by multidrug-resistant (MDR) – Sphingomonas paucimobilis

Sphyngomonas paucimobilis (S. paucimobilis) is a low-pathogenicity, gram-negative bacilli (GNB) that are previously known as an opportunist microorganism. Recent studies have shown that S. paucimobilis is an emerging pathogen causing various infections. Multidrug-resistant GNB has emerged as a major...

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Bibliographic Details
Published in:IDCases 2021-01, Vol.24, p.e01152, Article e01152
Main Authors: Saboe, Aninka, Adrian, Yudri, Widyatmoko, Leonardus, Hasan, Melawati, Cool, Charlotte Johanna, Hartantri, Yovita, Rahmadi, Andri Reza, Nusjirwan, Rama, Akbar, Mohammad Rizki
Format: Article
Language:English
Subjects:
Case Report
Multivalvular involvement
Perivalvular extension
Septic arthritis
Sphingomonas paucimobilis
Valve dehiscence
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Summary:Sphyngomonas paucimobilis (S. paucimobilis) is a low-pathogenicity, gram-negative bacilli (GNB) that are previously known as an opportunist microorganism. Recent studies have shown that S. paucimobilis is an emerging pathogen causing various infections. Multidrug-resistant GNB has emerged as a major clinical and therapeutic dilemma in various hospital-associated infections. Although rare, S. paucimobilis could be associated with infective endocarditis (IE). Prosthetic valve endocarditis (PVE) is the most severe type of IE, which has high mortality rates despite diagnostic and treatment advances. We report a fatal case of early PVE associated with multidrug-resistant (MDR) - S. paucimobilis complicated with perivalvular abscess, complete heart block, valve detachment, and septic arthritis.
ISSN:2214-2509
2214-2509
DOI:10.1016/j.idcr.2021.e01152