Optical Coherence Tomography Angiography Findings in Ocular Toxoplasmosis with Multiple Recurrences

Ocular toxoplasmosis is the most common cause of posterior uveitis that is caused by infection. Humans can be infected congenitally or postnatally. The typical lesion of ocular toxoplasmosis is focal necrotizing retinitis with overlying vitritis, which lead to hyperpigmented retinochoroidal scar at...

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Bibliographic Details
Published in:International medical case reports journal 2023-01, Vol.16, p.35-43
Main Authors: Sofia, Ovi, Wahyudi, I Nyoman Surya Ari, Fitri, Loeki Enggar, Prayitnaningsih, Seskoati, Susianti, Hani
Format: Article
Language:English
Subjects:
Angiography
Case reports
Case Series
Congenital diseases
Disease
Infection
Infections
Medical imaging
ocular toxoplasmosis
Ophthalmology
optical coherence tomography angiography
Outpatient care facilities
Physiological aspects
recurrent
retinochoroiditis
Tomography
Toxoplasmosis
Toxoplasmosis, Ocular
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Summary:Ocular toxoplasmosis is the most common cause of posterior uveitis that is caused by infection. Humans can be infected congenitally or postnatally. The typical lesion of ocular toxoplasmosis is focal necrotizing retinitis with overlying vitritis, which lead to hyperpigmented retinochoroidal scar at resolution of lesion. Macula involvement can cause substantial visual impairment. The high incidence of disease reactivation may lead to greater risk of vision loss. Optical coherence tomography angiography (OCTA) is a non-invasive imaging method to visualize the vascular and density perfusion of the retina and choroid, which cannot be obtained by conventional Optical Coherence Tomography (OCT). In this case report, we present two cases of active ocular toxoplasmosis with multiple recurrences to study pathological changes in retinal and choroidal microvasculature. The findings reveal the involvement of all of the retinal layers in the choroid, with distinct changes in the deep retinal layer.
ISSN:1179-142X
1179-142X
DOI:10.2147/IMCRJ.S395600