Mediating role of depressive symptoms on the relationship between sleep duration and cognitive function

• Published in: Scientific reports 2023-03, Vol.13 (1), p.4067-9, Article 4067
• Main Authors: Wang, Liqun, He, Shulan, Yan, Ning, Pan, Ruiping, Niu, Yang, Li, Jiangping
• Format: Article
• Language: English
• Subjects: 692/308; 692/499; 692/699; 692/700; Cognition; Cognition & reasoning; Cognitive ability; Cognitive Dysfunction; Cross-Sectional Studies; Depression - psychology; Epidemiology; Humanities and Social Sciences; Humans; Mental depression; multidisciplinary; Population studies; Regression analysis; Science; Science (multidisciplinary); Sleep; Sleep Duration; Spatial memory; Visual perception
• ISSN: 2045-2322; 2045-2322
• DOI: 10.1038/s41598-023-31357-6

Although some studies have shown the association between sleep duration and cognitive impairment is positive, the mechanism explaining how sleep duration is linked to cognition remains poor understood. The current study aims to explore it among Chinese population. A cross-sectional study of 12,589 participants aged 45 or over was conducted, cognition was assessed by three measures to capture mental intactness, episodic memory, and visuospatial abilities. The Center for Epidemiologic Studies Depression Scale 10 (CES-D 10 ) was administered during the face-to-face survey to assess depressive status. Sleep duration was reported by the participants themselves. Partial correlation and linear regression were used to explore the association between sleep duration, cognition, and depression. The Bootstrap methods PROCESS program was used to detect the mediation effect of depression. Sleep duration was positively correlated with cognition and negatively with depression ( p