Serum lactate levels in critically Ill patients: An early marker to be targeted

Hyperlactatemia (excess blood lactate) is common in severely unwell individuals. Although lactate levels are routinely used to indicate insufficient tissue oxygenation, they can also be elevated by mechanisms unrelated to tissue oxygenation. Increased glycolysis may be a major cause of hyperlactatem...

Full description

Saved in:
Bibliographic Details
Published in:Journal of the scientific society (Belgaum) 2022-09, Vol.49 (3), p.246-250
Main Authors: Kabra, Ruchita, Acharya, Sourya, Kumar, Sunil
Format: Article
Language:English
Subjects:
Acidosis
Blood
Care and treatment
Critically ill
critically sick
Diagnosis
Glycolysis
Health aspects
Hyperlactatemia
Lactates
Lactic acid
Lactic acidosis
Measurement
Medical examination
Metabolic diseases
Morbidity
Oxygenation
Prognosis
Resuscitation
Risk factors
Citations: Items that this one cites
Items that cite this one
Online Access:Get full text
Tags: Add Tag
No Tags, Be the first to tag this record!
Description
Summary:Hyperlactatemia (excess blood lactate) is common in severely unwell individuals. Although lactate levels are routinely used to indicate insufficient tissue oxygenation, they can also be elevated by mechanisms unrelated to tissue oxygenation. Increased glycolysis may be a major cause of hyperlactatemia, especially in critically sick individuals. Despite this, elevated lactate levels have serious consequences for the morbidity and mortality of hyperlactatemia individuals. Despite the widespread use of the phrase lactic acidosis, a substantial link between lactate and pH appears only at higher lactate levels. As a result, the phrase lactate-related acidosis is more suitable. In early resuscitation, two recent studies have emphasized the necessity of monitoring lactate levels and adjusting treatment to changes in lactate levels. Structured lactate measures should be included in resuscitation protocols since lactate levels may be assessed quickly at the bedside from a variety of sources.
ISSN:0974-5009
2278-7127
DOI:10.4103/jss.jss_113_22