4013 Does dietary fat composition predict short-term elevations in lipid levels in adults on a modified Atkins diet?

OBJECTIVES/GOALS: The modified Atkins diet (MAD) is used in the management of drug-resistant epilepsy in adults. Some patients on MAD show an increase in serum levels of total cholesterol and low-density lipoprotein (LDL) cholesterol. We explored whether dietary fat composition predicts short-term e...

Full description

Saved in:
Bibliographic Details
Published in:Journal of clinical and translational science 2020-06, Vol.4 (s1), p.28-28
Main Authors: McDonald, Tanya, Henry-Barron, Bobbie J, Vizthum, Diane, Cervenka, Mackenzie C.
Format: Article
Language:English
Subjects:
Cholesterol
Clinical Epidemiology/Clinical Trial
Diet
Drug resistance
Epilepsy
Fatty acids
Food intake
Grants
High density lipoprotein
Lipids
Low density lipoprotein
Medical research
Nutrition research
Oils & fats
Patients
Polyunsaturated fatty acids
Population studies
Serum levels
Translation
Triglycerides
Online Access:Get full text
Tags: Add Tag
No Tags, Be the first to tag this record!
Description
Summary:OBJECTIVES/GOALS: The modified Atkins diet (MAD) is used in the management of drug-resistant epilepsy in adults. Some patients on MAD show an increase in serum levels of total cholesterol and low-density lipoprotein (LDL) cholesterol. We explored whether dietary fat composition predicts short-term elevations in serum lipid levels in diet-naïve adults who begin MAD. METHODS/STUDY POPULATION: Participants self-reported their diet intake with 3-day food records at baseline, 1 month and 2 months. Food records were analyzed using Nutrition Data System for Research software. Fasting serum levels of total cholesterol (TC), high-density lipoprotein (HDL) cholesterol, and triglycerides were also collected and LDL level calculated at baseline, 1 month, and 2 months. RESULTS/ANTICIPATED RESULTS: 38 patients submitted complete food records at each study visit (baseline, 1 month, and 2 month). Compared to baseline diet intake, there was a significant reduction in daily carbohydrate intake at 1 and 2 months months (p
ISSN:2059-8661
2059-8661
DOI:10.1017/cts.2020.122