Efficient synthesis of vitamin D3 in a 3D ultraviolet photochemical microreactor fabricated using an ultrafast laser

Large-scale, high-precision, and high-transparency microchannels hold great potential for developing high-performance continuous-flow photochemical reactions. We demonstrated ultrafast laser-enabled fabrication of three-dimensional microchannel reactors in ultraviolet (UV) grade fused silica which e...

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Bibliographic Details
Published in:Light: advanced manufacturing 2024-01, Vol.5, p.1-9
Main Authors: Aodong Zhang, Jian Xu, Lingling Xia, Ming Hu, Yunpeng Song, Miao Wu, Ya Cheng
Format: Article
Language:English
Subjects:
continuous-flow synthesis
fused silica microchannels
ultrafast laser microfabrication
uv photochemical reactors
vitamin d3
Online Access:Get full text
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Summary:Large-scale, high-precision, and high-transparency microchannels hold great potential for developing high-performance continuous-flow photochemical reactions. We demonstrated ultrafast laser-enabled fabrication of three-dimensional microchannel reactors in ultraviolet (UV) grade fused silica which exhibit high transparency under the illumination of UV light sources of wavelengths well below 300 nm with excellent mixing efficiency. With the fabricated glass microchannel reactors, we demonstrated continuous-flow photochemical synthesis of vitamin D3 with UV LED array light sources.
ISSN:2689-9620
DOI:10.37188/lam.2024.010