Application of anatomy unit resection surgery for lateral basicranial surgical approach in oral squamous carcinoma

• Published in: BMC oral health 2023-01, Vol.23 (1), p.9-9, Article 9
• Main Authors: Wu, Kun, Liu, Ke-Yue, Gong, Zhao-Jian, Zhang, Sheng, Ren, Zhen-Hu, Wu, Han-Jiang
• Format: Article
• Language: English
• Subjects: Anatomy unit resection surgery; Carcinoma, Squamous Cell - pathology; Head and Neck Neoplasms - pathology; Humans; Lateral basicranial surgical approach; Mouth Neoplasms - pathology; Mouth Neoplasms - surgery; Neoplasm Staging; Overall survival rate; Posterior oral squamous cell carcinoma; Prognosis; Retrospective Studies; Squamous Cell Carcinoma of Head and Neck - pathology; Treatment Outcome
• ISSN: 1472-6831; 1472-6831
• DOI: 10.1186/s12903-023-02708-6

The basicranial region lacks definite boundaries and includes various anatomical units. We developed a novel concept of the posterior oral anatomical complex (POAC) to identify these anatomical units in the basicranial region. OSCC with POAC involvement is termed posterior oral squamous cell carcinoma (POSCC) with poor prognosis. The principal aim of this study was to evaluate the effect of anatomy unit resection surgery (AUSR) on patients with POSCC. A total of 120 POSCC patients who underwent radical surgical treatment were recruited for this study. These POSCC patients were treated with conventional surgery or AUSR. According to the extent of primary tumor resection in the AUSR group, the lateral basicranial surgical approach can be subdivided into four types: face-lateral approach I, face-lateral approach II, face-median approach or face-median and face-lateral combined approach. Facial nerve function was evaluated according to the House-Brackmann Facial Nerve Grading System. The overall survival rate was 62.5% and 37.5% in the AURS group and conventional group (hazard ratio: 0.59; p