A Cruciform Petal-like (ZIF-8) with Bactericidal Activity against Foodborne Gram-Positive Bacteria for Antibacterial Food Packaging

• Published in: International journal of molecular sciences 2022-07, Vol.23 (14), p.7510
• Main Authors: Shen, Bowen, Wang, Yuxian, Wang, Xinlong, Amal, Fatima Ezzahra, Zhu, Liying, Jiang, Ling
• Format: Article
• Language: English
• Subjects: antibacterial; Antibacterial activity; Antibacterial materials; Aqueous solutions; Bacteria; Bactericidal activity; Catalytic activity; Cell walls; cruciform petal-like ZIF-8; Disinfection; Drug resistance; E coli; food packaging; food preservation; Food safety; foodborne bacteria; Gram-negative bacteria; Gram-positive bacteria; Imidazole; Ligands; Light; Membranes; Morphology; Nanomaterials; Nanotechnology; Permeability; Personal health; Petals; Photocatalysis; Reactive oxygen species; Staphylococcus aureus; ZIF-8-Film; Zinc
• ISSN: 1422-0067; 1661-6596; 1422-0067
• DOI: 10.3390/ijms23147510

Most antibacterial nanomaterials used in food packaging act by releasing reactive oxygen species (ROS), which cannot efficiently have an inhibitory effect by penetrating the cell wall of Gram-positive Staphylococcus aureus. In this work, we used the cruciform petal-like zeolite imidazole framework-8 (ZIF-8) synthesized in the water phase which can release active Zn compounds in aqueous solution and exert a stronger inhibitory effect on S. aureus. The experimental results demonstrated that the aqueous cruciform petal-like ZIF-8 has the same photocatalytic activity as traditional ZIF-8 and can be applied in photocatalytic bacterial inactivation. The cruciform petal-like ZIF-8 was also shown to release active Zn compounds in aqueous solution with a better antibacterial effect against S. aureus, reaching 95% inactivation efficiency. The antibacterial effect was therefore 70% higher than that of traditional ZIF-8. Based on its excellent antibacterial properties, we loaded petal-like ZIF-8, PDA and PVA onto ordinary fibers to prepare ZIF-8-Film. The results further showed that ZIF-8-Film has a high filtration capacity, which can be used in antibacterial packaging material with the required air permeability. Moreover, ZIF-8-Flim can clean the surface on its own and can maintain a sterile environment. It is different from other disposable materials on the market in that it can be reused and has a self-disinfection function.