Risk factors for chronic obstructive pulmonary disease among never-smokers in Korea

Chronic obstructive pulmonary disease (COPD) patients include those who have never smoked. However, risk factors other than smoking in never-smokers have not been elucidated sufficiently. This study investigated the risk factors for COPD among never-smokers in Korea using population-based data. The...

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Bibliographic Details
Published in:International journal of chronic obstructive pulmonary disease 2015-01, Vol.10 (Issue 1), p.497-506
Main Authors: Lee, Seok Jeong, Kim, Seo Woo, Kong, Kyoung Ae, Ryu, Yon Ju, Lee, Jin Hwa, Chang, Jung Hyun
Format: Article
Language:English
Subjects:
Adult
Age Factors
Aged
Aged, 80 and over
Body mass index
Bronchiectasis - epidemiology
Chi-Square Distribution
Chronic obstructive lung disease
Chronic obstructive pulmonary disease
Comorbidity
Female
Health aspects
Health Surveys
Humans
Logistic Models
Male
Middle Aged
Mycobacterium
Nonsmokers
Odds Ratio
Original Research
Public health administration
Pulmonary Disease, Chronic Obstructive - diagnosis
Pulmonary Disease, Chronic Obstructive - epidemiology
Republic of Korea - epidemiology
Risk Factors
Sex Factors
Socioeconomic Factors
Surveys and Questionnaires
Thinness - epidemiology
Tuberculosis
Tuberculosis, Pulmonary - epidemiology
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Summary:Chronic obstructive pulmonary disease (COPD) patients include those who have never smoked. However, risk factors other than smoking in never-smokers have not been elucidated sufficiently. This study investigated the risk factors for COPD among never-smokers in Korea using population-based data. The data were retrieved from the Korean National Health and Nutrition Survey IV conducted from 2007 to 2009. Among subjects aged 40 years or older who underwent appropriate pulmonary function tests, never-smokers not diagnosed with asthma and not showing a restrictive pattern on pulmonary function tests were enrolled. Risk factors of COPD in never-smokers were analyzed using logistic regression models. Among 24,871 participants in the representative Korean cohort, 3,473 never-smokers were enrolled. COPD patients accounted for 7.6% of the never-smokers. In the logistic regression analysis, low education status (odds ratio [OR]: 2.0; 95% confidence interval [CI]: 1.2-3.2), occupational exposure (OR: 2.6; 95% CI: 1.3-5.3), a history of tuberculosis (OR: 4.5; 95% CI: 2.3-8.7), bronchiectasis (OR: 6.0; 95% CI: 1.4-25.4), male sex (OR: 4.2; 95% CI: 2.6-6.7), advanced age (60-69 years vs 40-49 years; OR: 3.8; 95% CI: 2.0-7.0), and being underweight (body mass index
ISSN:1178-2005
1176-9106
1178-2005
DOI:10.2147/COPD.S77662