Colon metastasis from hepatocellular carcinoma: a case report and literature review

Hepatocellular carcinoma (HCC) is a malignant tumor with frequent intrahepatic metastases; extrahepatic metastases are not rare but less frequent compared to intrahepatic ones. The most frequent sites of extrahepatic metastases are the lungs, followed by the lymph nodes, bones, and adrenal glands. C...

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Bibliographic Details
Published in:World journal of surgical oncology 2020-07, Vol.18 (1), p.189-189, Article 189
Main Authors: Yu, Yong-Ming, Cao, Yi-Sheng, Wu, Zhou, Huang, Rong, Shen, Zhong-Lei
Format: Article
Language:English
Subjects:
Abdomen
Ablation
Adrenal glands
Antigens
Bones
Cancer metastasis
Carcinoma, Hepatocellular - therapy
Care and treatment
Case Report
Case reports
Case studies
Chemoembolization, Therapeutic
Colon
Colon cancer
Complications and side effects
Computed tomography
Development and progression
Gastrointestinal tract
Hepatitis B
Hepatocellular carcinoma
Hospitals
Humans
Immunohistochemistry
Implantation
Literature reviews
Liver cancer
Liver Neoplasms - therapy
Lungs
Lymph nodes
Lymphatic system
Magnetic resonance imaging
Male
Medical imaging
Metastases
Metastasis
Middle Aged
Patients
Prognosis
Risk analysis
Risk factors
Surgery
Tumors
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Items that cite this one
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Summary:Hepatocellular carcinoma (HCC) is a malignant tumor with frequent intrahepatic metastases; extrahepatic metastases are not rare but less frequent compared to intrahepatic ones. The most frequent sites of extrahepatic metastases are the lungs, followed by the lymph nodes, bones, and adrenal glands. Case report covering gastrointestinal (GI) tract involvement from HCC is limited. A 60-year-old man was referred to us in May 2019 with a diagnosis of sigmoid colon tumor. The patient had a history of HCC and had received two stages of open resections for the primary and the abdominal metastasis successively and many times of transcatheter arterial chemoembolization (TACE). The sigmoid colon tumor received Hartmann procedure after abdominal enhanced computerized tomography (CT) scan and colonoscopy, while postoperative pathology and immunohistochemistry identified it as extrahepatic colonic metastasis from HCC. The ratio of extrahepatic metastasis to the digestive tract was very low, and the majority was upper gastrointestinal involvement because of direct invasion or intraperitoneal implantation. TACE may be the risk factor of retrograde hematogenous metastasis to the downstream colon.
ISSN:1477-7819
1477-7819
DOI:10.1186/s12957-020-01960-2