Effect of microencapsulation on Saccharomyces cerevisiae var. boulardii viability in the gastrointestinal tract and level of some blood biochemical factors in wistar rats

Probiotics are live microorganisms that, when administered in an adequate amount, confer a health benefit on the host through the gut. is a widespread yeast found in nature. This microorganism has been used as a probiotic agent in recent years. In this study, the effect of microencapsulation on surv...

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Bibliographic Details
Published in:Iranian journal of microbiology 2019-04, Vol.11 (2), p.160-165
Main Authors: Ghorbani-Choboghlo, Hassan, Nikaein, Donya, Khosravi, Ali-Reza, Rahmani, Reza, Farahnejad, Zohreh
Format: Article
Language:English
Subjects:
Blood biochemical factors
Microencapsulation
Original
Probiotic
Saccharomyces cerevisiae var. boulardii
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Summary:Probiotics are live microorganisms that, when administered in an adequate amount, confer a health benefit on the host through the gut. is a widespread yeast found in nature. This microorganism has been used as a probiotic agent in recent years. In this study, the effect of microencapsulation on survival rate of in the simulated gastrointestinal tract medium and the impact of microencapsulated on some serum biochemical factors in a rat model was evaluated. 30 male wistar rats were divided into three groups (control, rats receiving microencapsulated , and rats receiving alone). The probiotic was gavaged at a dosage of 2 gr/kg BW for 8 weeks. Blood was collected from rats at the end of the treatment period and biochemical factors were measured using Mancompany kits. The results showed a significant increase in viability of microencapsulated in comparison with free (p
ISSN:2008-3289
2008-4447
DOI:10.18502/ijm.v11i2.1082