Analysis of the immune response using FTIR spectroscopy in mothers and their newborns with different vaccination schemes for COVID-19

The SARS-CoV-2 outbreak has provoked more than 6 million deaths worldwide. The scarcity of effective treatments and its virulence converted the vaccines into an essential tool to face it. The most used vaccines were the mRNA, adenovirus vector, and inactivated whole-virus. However, nowadays, infants...

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Bibliographic Details
Published in:Scientific reports 2024-07, Vol.14 (1), p.17308-15, Article 17308
Main Authors: Mata-Miranda, Monica M., Martinez-Cuazitl, Adriana, Gutierrez-Cortes, Hermes, Cordero-Hernandez, Librado, Guerrero-Ruiz, Melissa, Lopez-Reyes, Alberto, Rodriguez-Baez, Alvaro, Vazquez-Zapien, Gustavo J.
Format: Article
Language:English
Subjects:
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Adult
Antibodies, Viral - analysis
Antibodies, Viral - blood
Antibodies, Viral - immunology
COVID-19
COVID-19 - immunology
COVID-19 - prevention & control
COVID-19 vaccines
COVID-19 Vaccines - immunology
Female
Humanities and Social Sciences
Humans
Humoral immunity
Immune response
Immune response (cell-mediated)
Immune response (humoral)
Immunity (passive)
Immunity, Cellular
Immunity, Humoral
Immunization
Immunoglobulin A
Immunoglobulin A - analysis
Immunoglobulin A - immunology
Immunoglobulin G
Immunoglobulin G - blood
Immunoglobulin G - immunology
Infant, Newborn
Interferon-gamma - metabolism
Mothers
mRNA
mRNA vaccines
mRNA Vaccines - immunology
multidisciplinary
Neonates
Pregnancy
Saliva
Saliva - immunology
SARS-CoV-2 - immunology
Science
Science (multidisciplinary)
Severe acute respiratory syndrome coronavirus 2
Spectroscopy
Spectroscopy, Fourier Transform Infrared - methods
Spectrum analysis
Statistical analysis
Vaccination - methods
Vaccines
Virulence
γ-Interferon
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Description
Summary:The SARS-CoV-2 outbreak has provoked more than 6 million deaths worldwide. The scarcity of effective treatments and its virulence converted the vaccines into an essential tool to face it. The most used vaccines were the mRNA, adenovirus vector, and inactivated whole-virus. However, nowadays, infants aged 
ISSN:2045-2322
2045-2322
DOI:10.1038/s41598-024-68340-8