The Potential Prognostic Marker TyG Index Predicts Time to Brain Metastasis at HER2 Positive Breast Cancer

We aimed to investigate the prognostic significance of insulin resistance (IR) markers fasting triglyceride-glucose (TyG) index and triglyceride high-density lipoprotein cholesterol (TG/HDL-C) ratio in HER2-positive breast cancer (BC) patients with brain metastasis (BM). In this single-center study,...

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Bibliographic Details
Published in:Cancer management and research 2023-01, Vol.15, p.311-317
Main Authors: Karadag, Ibrahim, Karakaya, Serdar, Akkan, Tolga, Demir, Bilgin, Alkurt, Ertugrul Gazi, Dogan, Mutlu
Format: Article
Language:English
Subjects:
Analysis
brain metastasis
Breast cancer
Cancer patients
Cholesterol
Dextrose
Glucose
Glucose metabolism
glucose-lipid metabolism
her2 positive breast cancer
Insulin resistance
Medical research
Medicine, Experimental
Metastasis
Original Research
Physiological aspects
Prognosis
Risk factors
tg/hdl-c ratio
Triglycerides
tyg index
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Summary:We aimed to investigate the prognostic significance of insulin resistance (IR) markers fasting triglyceride-glucose (TyG) index and triglyceride high-density lipoprotein cholesterol (TG/HDL-C) ratio in HER2-positive breast cancer (BC) patients with brain metastasis (BM). In this single-center study, 120 patients who met the criteria were included. TyG and TG/HDL-C at the time of diagnosis were computed retrospectively. For TyG and TG/HDL-C, the median values of 9.32 and 2.95 were taken as the cut-off, respectively. TyG values
ISSN:1179-1322
1179-1322
DOI:10.2147/CMAR.S403445