Characterization, stability and antioxidant activity of curcumin nanocomplexes with soy protein isolate and pectin

Curcumin (Cur) has antioxidant, anti-inflammatory and other biological activities, but its poor stability, low water solubility and other defects limit the application. Herein, Cur was nanocomposited with soy isolate protein (SPI) and pectin (PE) for the first time and its characterization, bioavail...

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Bibliographic Details
Published in:Current research in food science 2023-01, Vol.6, p.100530-100530, Article 100530
Main Authors: Fu, Lijuan, Tan, Suo, Si, Ruiru, Qiang, Yueyue, Wei, Hang, Huang, Biao, Shi, Mengzhu, Fang, Ling, Fu, Jianwei, Zeng, Shaoxiao
Format: Article
Language:English
Subjects:
Antioxidant activity
Curcumin
Nanocomplexes
Pectin
Soy protein isolate
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Summary:Curcumin (Cur) has antioxidant, anti-inflammatory and other biological activities, but its poor stability, low water solubility and other defects limit the application. Herein, Cur was nanocomposited with soy isolate protein (SPI) and pectin (PE) for the first time and its characterization, bioavailability and antioxidant activity were discussed. The optimal encapsulation process of SPI-Cur-PE was as follow: the addition amount of PE was 4 mg, Cur was 0.6 mg and at pH of 7. It was observed by SEM that SPI-Cur-PE were partially aggregated. The average particle size of SPI-Cur-PE was 210.1 nm and the zeta potential was −31.99 mV. Through XRD, FT-IR and DSC analysis, the SPI-Cur-PE was formed through hydrophobic interaction and electrostatic interaction. The SPI-Cur-PE released more slowly in simulated gastrointestinal treatment and displayed higher photostability and thermal stability. SPI-Cur-PE, SPI-Cur and free Cur had scavenging activities for 2,2′-azino-bis (3-ethylbenzothiazoline-6-sulfonic acid) (ABTS) and 1,1-diphenyl-2-picryl-hydrazyl (DPPH) radicals. [Display omitted] •The SPI-Cur-PE nanocomplexes were prepared successfully for the first time.•The thermal stability and photostability of SPI-Cur-PE were higher than that of free Cur.•SPI-Cur-PE shown lower releasing speed than SPI-Cur and free Cur in vitro release test.•The release rate of SPI-Cur-PE in SGF was lower than that of SPI-Cur and free Cur.•The SPI-Cur-PE represented significantly scavenging activity of ABTS and DPPH radicals.
ISSN:2665-9271
2665-9271
DOI:10.1016/j.crfs.2023.100530