Patient-Reported Quality of Life Before and After Total Knee Arthroplasty: A Multicenter Observational Study

To compare patients' self-reported health-related quality of life (HRQoL) before and after total knee arthroplasty (TKA) and determine factors contributing to any heterogeneity in HRQoL. This prospective multicenter observational study included 404 patients with knee osteoarthritis who underwen...

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Bibliographic Details
Published in:Patient preference and adherence 2022-01, Vol.16, p.737-748
Main Authors: Chang, Jinghui, Fu, Manru, Cao, Peihua, Ding, Changhai, Wang, Dong
Format: Article
Language:English
Subjects:
Arthritics
Care and treatment
Health aspects
knee function
knee osteoarthritis
knee replacement
Original Research
Osteoarthritis
Quality of life
Surveys
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Summary:To compare patients' self-reported health-related quality of life (HRQoL) before and after total knee arthroplasty (TKA) and determine factors contributing to any heterogeneity in HRQoL. This prospective multicenter observational study included 404 patients with knee osteoarthritis who underwent TKA between April 1, 2019 and December 30, 2019 and whose HRQoL was assessed preoperatively and 7 days and 1, 3, and 6 months postoperatively. Sociodemographic characteristics were assessed using a General Information Questionnaire, disability using the Knee Injury and Osteoarthritis Outcome Score (KOOS-PS), resting pain using the visual analogue scale (Pain-VAS), and HRQoL using the European Quality of Life Five Dimension Five Level (EQ-5D-5L) scale. The growth mixture model was used to identify group heterogeneity in the developmental trajectories of KOOS-PS, Pain-VAS, and EQ5D5L. Logistic regression was used to explore the factors influencing the developmental trajectories of factors affecting the developmental trajectory of HRQoL. The mean EQ-5D-5L score improved from 0.69 preoperatively to 0.90 at 6 months postoperatively. Longitudinal heterogeneity in HRQoL was observed in patients during recovery: 1) patients with a small and slow improvement in HRQoL and 2) patients who showed marked and rapid improvement in HRQoL. The main characteristics of the latter group were decreasing VAS pain scores, a monthly family income >2000 CNY (100 CNY equals approximately 14.9 USD), exercising for
ISSN:1177-889X
1177-889X
DOI:10.2147/PPA.S357632