A Multiscale Approach for Predicting Certain Effects of Hand-Transmitted Vibration on Finger Arteries

• Published in: Vibration 2022-06, Vol.5 (2), p.213-237
• Main Authors: Noël, Christophe, Settembre, Nicla, Reda, Maha, Jacquet, Emmanuelle
• Format: Article
• Language: English
• Subjects: Arteries; Biological models (mathematics); Biomechanics; Cardiology and cardiovascular system; Employees; Endothelium; Exposure; fluid–structure interaction; Hand (anatomy); Hand-arm vibration syndrome; Human health and pathology; Life Sciences; Matrix metalloproteinases; Mechanics; Multiscale analysis; Physics; Physiology; proper volar artery; pulsatile flow; Shear forces; Shear stress; ultrasound; Veins & arteries; Vibration; Vibration White Finger; Vibrations; Wall Shear Stress; Wall shear stresses
• ISSN: 2571-631X; 2571-631X
• DOI: 10.3390/vibration5020014

Prolonged exposure to strong hand-arm vibrations can lead to vascular disorders such as Vibration White Finger (VWF). We modeled the onset of this peripheral vascular disease in two steps. The first consists in assessing the reduction in shearing forces exerted by the blood on the walls of the arteries (Wall Shear Stress—WSS) during exposure to vibrations. An acute but repeated reduction in WSS can lead to arterial stenosis characteristic of VWF. The second step is devoted to using a numerical mechano-biological model to predict this stenosis as a function of WSS. WSS is reduced by a factor of 3 during exposure to vibration of 40 m·s−2. This reduction is independent of the frequency of excitation between 31 Hz and 400 Hz. WSS decreases logarithmically when the amplitude of the vibration increases. The mechano-biological model simulated arterial stenosis of 30% for an employee exposed for 4 h a day for 10 years. This model also highlighted the chronic accumulation of matrix metalloproteinase 2. By considering daily exposure and the vibratory level, we can calculate the degree of stenosis, thus that of the disease for chronic exposure to vibrations.