Quadriceps muscle properties in rheumatoid arthritis: insights about muscle morphology, activation and functional capacity

Rheumatoid arthritis (RA) is an inflammatory and chronic autoimmune disease that leads to muscle mass loss and functional capacity impairment, potentiated by physical inactivity. Despite evidences demonstrate neuromuscular impairments in RA patients, aging effects may have masked the results of simi...

Full description

Saved in:
Bibliographic Details
Published in:Advances in rheumatology (London, England) England), 2020-05, Vol.60 (1), p.28-28, Article 28
Main Authors: Blum, Denise, Rodrigues, Rodrigo, Geremia, Jeam Marcel, Brenol, Claiton Viegas, Vaz, Marco Aurélio, Xavier, Ricardo Machado
Format: Article
Language:English
Subjects:
Activities of daily living
Aging
Arthritis, rheumatoid
Autoimmune diseases
Chronic obstructive pulmonary disease
Data collection
Disease
Electromyography
Knee
Morphology
Muscle contraction
Muscle strength
Muscular atrophy
Pain
Physical activity
Quadriceps muscle
Questionnaires
Rheumatoid arthritis
RHEUMATOLOGY
Ultrasonic imaging
Citations: Items that this one cites
Items that cite this one
Online Access:Get full text
Tags: Add Tag
No Tags, Be the first to tag this record!
Description
Summary:Rheumatoid arthritis (RA) is an inflammatory and chronic autoimmune disease that leads to muscle mass loss and functional capacity impairment, potentiated by physical inactivity. Despite evidences demonstrate neuromuscular impairments in RA patients, aging effects may have masked the results of similar previous studies. The aim of study was to verify (i) the effects of RA on functional capacity and muscle properties in middle-aged patients and (ii) the association between age, clinical characteristics, quadriceps muscle properties and functional capacity. Thirty-five RA women and 35 healthy age-matched women were compared with the following outcomes: (i) physical activity level through the International Physical Activity Questionnaire (IPAQ); (ii) timed-up and go (TUG) test; (iii) isometric knee extensor muscular strength; and (iv) vastus lateralis muscle activation and muscle architecture (muscle thickness, pennation angle and fascicle length) during an isometric test. An independent Student t-test and partial correlation (controlled by physical activity levels) were performed, with p 
ISSN:2523-3106
2523-3106
DOI:10.1186/s42358-020-00132-w