Loading…

Mycobacterium leprae on Palatine Tonsils and Adenoids of Asymptomatic Patients, Brazil

We investigated palatine tonsil and adenoid specimens excised from otorhinolaryngological patients in a leprosy-endemic region of Brazil. Fite-Faraco staining identified Mycobacterium spp. in 9 of 397 specimen blocks. Immunohistochemistry and molecular analysis confirmed the presence of Mycobacteriu...

Full description

Saved in:
Bibliographic Details
Published in:Emerging infectious diseases 2020-10, Vol.26 (10), p.2518-2520
Main Authors: Morgado de Abreu, Marilda Aparecida Milanez, Nai, Gisele Alborghetti, Molina, Juliana D'Andrea, Gomes, Rafael Tomaz, Paula, Natalia de, Roselino, Ana Maria
Format: Article
Language:English
Subjects:
Citations: Items that this one cites
Items that cite this one
Online Access:Get full text
Tags: Add Tag
No Tags, Be the first to tag this record!
cited_by cdi_FETCH-LOGICAL-c688t-f2f06d3e1a692c4d058fddbbf932b0e397b0de0975a4de10f144a9d9d9f5d6993
cites cdi_FETCH-LOGICAL-c688t-f2f06d3e1a692c4d058fddbbf932b0e397b0de0975a4de10f144a9d9d9f5d6993
container_end_page 2520
container_issue 10
container_start_page 2518
container_title Emerging infectious diseases
container_volume 26
creator Morgado de Abreu, Marilda Aparecida Milanez
Nai, Gisele Alborghetti
Molina, Juliana D'Andrea
Gomes, Rafael Tomaz
Paula, Natalia de
Roselino, Ana Maria
description We investigated palatine tonsil and adenoid specimens excised from otorhinolaryngological patients in a leprosy-endemic region of Brazil. Fite-Faraco staining identified Mycobacterium spp. in 9 of 397 specimen blocks. Immunohistochemistry and molecular analysis confirmed the presence of Mycobacterium leprae, indicating that these organs can house M. leprae in persons inhabiting a leprosy-endemic region.
doi_str_mv 10.3201/eid2610.191267
format article
fullrecord <record><control><sourceid>gale_doaj_</sourceid><recordid>TN_cdi_doaj_primary_oai_doaj_org_article_2808684ccf96406ebfd18c0172e32696</recordid><sourceformat>XML</sourceformat><sourcesystem>PC</sourcesystem><galeid>A638989143</galeid><doaj_id>oai_doaj_org_article_2808684ccf96406ebfd18c0172e32696</doaj_id><sourcerecordid>A638989143</sourcerecordid><originalsourceid>FETCH-LOGICAL-c688t-f2f06d3e1a692c4d058fddbbf932b0e397b0de0975a4de10f144a9d9d9f5d6993</originalsourceid><addsrcrecordid>eNqNk01vEzEQhlcIREvhyhGthIRAIsX2er32BSlUfEQqKoLSq-W1x4mjXTvYu1XDr8dtQtSgHNAc_PXM6xmPpyieY3RaEYTfgTOE5QUWmLDmQXGMEUcThmrxcDen6Kh4ktISIZxdxOPiqCKCsoaw4-Lq61qHVukBohv7soNVVFAGX35TnRqch_Iy-OS6VCpvyqkBH5xJZbDlNK371RD6TOlMDw78kN6WH6L67bqnxSOrugTPtuNJ8fPTx8uzL5Pzi8-zs-n5RDPOh4klFjFTAVZMEE0Nqrk1pm2tqEiLoBJNiwwg0dSKGsDIYkqVMNlsbZgQ1Ukx2-iaoJZyFV2v4loG5eTdRohzqWIOsANJOOKMU62tYBQxaK3BXCPcEKgIEyxrvd9orca2B6NzPlF1e6L7J94t5Dxcy6bGiIk6C7zeCsTwa4Q0yN4lDV2nPIQxSUIprThCDcroy3_QZRijz0-VKZYfA_G77LbUXOUEnLch36tvReWUVVxwgWmVqckBag4ecpDBg3V5e48_PcBnM9A7fdDhzZ5DZga4GeZqTEnOfnz_f_biap99dY9dgOqGRQrdOLj85Q5GrGNIKYLdFQUjedsGctsGctMG2eHF_VLu8L__vvoDvKb-mg</addsrcrecordid><sourcetype>Open Website</sourcetype><iscdi>true</iscdi><recordtype>article</recordtype><pqid>2466920899</pqid></control><display><type>article</type><title>Mycobacterium leprae on Palatine Tonsils and Adenoids of Asymptomatic Patients, Brazil</title><source>PubMed Central</source><creator>Morgado de Abreu, Marilda Aparecida Milanez ; Nai, Gisele Alborghetti ; Molina, Juliana D'Andrea ; Gomes, Rafael Tomaz ; Paula, Natalia de ; Roselino, Ana Maria</creator><creatorcontrib>Morgado de Abreu, Marilda Aparecida Milanez ; Nai, Gisele Alborghetti ; Molina, Juliana D'Andrea ; Gomes, Rafael Tomaz ; Paula, Natalia de ; Roselino, Ana Maria</creatorcontrib><description>We investigated palatine tonsil and adenoid specimens excised from otorhinolaryngological patients in a leprosy-endemic region of Brazil. Fite-Faraco staining identified Mycobacterium spp. in 9 of 397 specimen blocks. Immunohistochemistry and molecular analysis confirmed the presence of Mycobacterium leprae, indicating that these organs can house M. leprae in persons inhabiting a leprosy-endemic region.</description><identifier>ISSN: 1080-6040</identifier><identifier>EISSN: 1080-6059</identifier><identifier>DOI: 10.3201/eid2610.191267</identifier><identifier>PMID: 32946726</identifier><language>eng</language><publisher>United States: U.S. National Center for Infectious Diseases</publisher><subject>Adenoids ; Antibodies ; Antimicrobial agents ; Asymptomatic ; Brazil - epidemiology ; Deoxyribonucleic acid ; DNA ; Drug resistance ; Epidemiology ; Hospitals ; Humans ; Immunohistochemistry ; infection ; Leprosy ; Leprosy - epidemiology ; Mycobacterium leprae ; Mycobacterium leprae - genetics ; on Palatine Tonsils and Adenoids of Asymptomatic Patients, Brazil ; Palatine Tonsil ; palatine tonsils ; Public health ; Research Letter ; Surveillance ; Tuberculosis</subject><ispartof>Emerging infectious diseases, 2020-10, Vol.26 (10), p.2518-2520</ispartof><rights>COPYRIGHT 2020 U.S. National Center for Infectious Diseases</rights><rights>Published 2020. This article is a U.S. Government work and is in the public domain in the USA.</rights><lds50>peer_reviewed</lds50><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c688t-f2f06d3e1a692c4d058fddbbf932b0e397b0de0975a4de10f144a9d9d9f5d6993</citedby><cites>FETCH-LOGICAL-c688t-f2f06d3e1a692c4d058fddbbf932b0e397b0de0975a4de10f144a9d9d9f5d6993</cites></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktopdf>$$Uhttps://www.ncbi.nlm.nih.gov/pmc/articles/PMC7510695/pdf/$$EPDF$$P50$$Gpubmedcentral$$Hfree_for_read</linktopdf><linktohtml>$$Uhttps://www.ncbi.nlm.nih.gov/pmc/articles/PMC7510695/$$EHTML$$P50$$Gpubmedcentral$$Hfree_for_read</linktohtml><link.rule.ids>230,314,727,780,784,885,27923,27924,53790,53792</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/32946726$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Morgado de Abreu, Marilda Aparecida Milanez</creatorcontrib><creatorcontrib>Nai, Gisele Alborghetti</creatorcontrib><creatorcontrib>Molina, Juliana D'Andrea</creatorcontrib><creatorcontrib>Gomes, Rafael Tomaz</creatorcontrib><creatorcontrib>Paula, Natalia de</creatorcontrib><creatorcontrib>Roselino, Ana Maria</creatorcontrib><title>Mycobacterium leprae on Palatine Tonsils and Adenoids of Asymptomatic Patients, Brazil</title><title>Emerging infectious diseases</title><addtitle>Emerg Infect Dis</addtitle><description>We investigated palatine tonsil and adenoid specimens excised from otorhinolaryngological patients in a leprosy-endemic region of Brazil. Fite-Faraco staining identified Mycobacterium spp. in 9 of 397 specimen blocks. Immunohistochemistry and molecular analysis confirmed the presence of Mycobacterium leprae, indicating that these organs can house M. leprae in persons inhabiting a leprosy-endemic region.</description><subject>Adenoids</subject><subject>Antibodies</subject><subject>Antimicrobial agents</subject><subject>Asymptomatic</subject><subject>Brazil - epidemiology</subject><subject>Deoxyribonucleic acid</subject><subject>DNA</subject><subject>Drug resistance</subject><subject>Epidemiology</subject><subject>Hospitals</subject><subject>Humans</subject><subject>Immunohistochemistry</subject><subject>infection</subject><subject>Leprosy</subject><subject>Leprosy - epidemiology</subject><subject>Mycobacterium leprae</subject><subject>Mycobacterium leprae - genetics</subject><subject>on Palatine Tonsils and Adenoids of Asymptomatic Patients, Brazil</subject><subject>Palatine Tonsil</subject><subject>palatine tonsils</subject><subject>Public health</subject><subject>Research Letter</subject><subject>Surveillance</subject><subject>Tuberculosis</subject><issn>1080-6040</issn><issn>1080-6059</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2020</creationdate><recordtype>article</recordtype><sourceid>DOA</sourceid><recordid>eNqNk01vEzEQhlcIREvhyhGthIRAIsX2er32BSlUfEQqKoLSq-W1x4mjXTvYu1XDr8dtQtSgHNAc_PXM6xmPpyieY3RaEYTfgTOE5QUWmLDmQXGMEUcThmrxcDen6Kh4ktISIZxdxOPiqCKCsoaw4-Lq61qHVukBohv7soNVVFAGX35TnRqch_Iy-OS6VCpvyqkBH5xJZbDlNK371RD6TOlMDw78kN6WH6L67bqnxSOrugTPtuNJ8fPTx8uzL5Pzi8-zs-n5RDPOh4klFjFTAVZMEE0Nqrk1pm2tqEiLoBJNiwwg0dSKGsDIYkqVMNlsbZgQ1Ukx2-iaoJZyFV2v4loG5eTdRohzqWIOsANJOOKMU62tYBQxaK3BXCPcEKgIEyxrvd9orca2B6NzPlF1e6L7J94t5Dxcy6bGiIk6C7zeCsTwa4Q0yN4lDV2nPIQxSUIprThCDcroy3_QZRijz0-VKZYfA_G77LbUXOUEnLch36tvReWUVVxwgWmVqckBag4ecpDBg3V5e48_PcBnM9A7fdDhzZ5DZga4GeZqTEnOfnz_f_biap99dY9dgOqGRQrdOLj85Q5GrGNIKYLdFQUjedsGctsGctMG2eHF_VLu8L__vvoDvKb-mg</recordid><startdate>202010</startdate><enddate>202010</enddate><creator>Morgado de Abreu, Marilda Aparecida Milanez</creator><creator>Nai, Gisele Alborghetti</creator><creator>Molina, Juliana D'Andrea</creator><creator>Gomes, Rafael Tomaz</creator><creator>Paula, Natalia de</creator><creator>Roselino, Ana Maria</creator><general>U.S. National Center for Infectious Diseases</general><general>Centers for Disease Control and Prevention</general><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>IOV</scope><scope>ISR</scope><scope>3V.</scope><scope>7RV</scope><scope>7X7</scope><scope>7XB</scope><scope>8C1</scope><scope>8FI</scope><scope>8FJ</scope><scope>8FK</scope><scope>ABUWG</scope><scope>AEUYN</scope><scope>AFKRA</scope><scope>AZQEC</scope><scope>BENPR</scope><scope>CCPQU</scope><scope>FYUFA</scope><scope>GHDGH</scope><scope>K9-</scope><scope>K9.</scope><scope>KB0</scope><scope>M0R</scope><scope>M0S</scope><scope>NAPCQ</scope><scope>PQEST</scope><scope>PQQKQ</scope><scope>PQUKI</scope><scope>PRINS</scope><scope>7X8</scope><scope>5PM</scope><scope>DOA</scope></search><sort><creationdate>202010</creationdate><title>Mycobacterium leprae on Palatine Tonsils and Adenoids of Asymptomatic Patients, Brazil</title><author>Morgado de Abreu, Marilda Aparecida Milanez ; Nai, Gisele Alborghetti ; Molina, Juliana D'Andrea ; Gomes, Rafael Tomaz ; Paula, Natalia de ; Roselino, Ana Maria</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c688t-f2f06d3e1a692c4d058fddbbf932b0e397b0de0975a4de10f144a9d9d9f5d6993</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2020</creationdate><topic>Adenoids</topic><topic>Antibodies</topic><topic>Antimicrobial agents</topic><topic>Asymptomatic</topic><topic>Brazil - epidemiology</topic><topic>Deoxyribonucleic acid</topic><topic>DNA</topic><topic>Drug resistance</topic><topic>Epidemiology</topic><topic>Hospitals</topic><topic>Humans</topic><topic>Immunohistochemistry</topic><topic>infection</topic><topic>Leprosy</topic><topic>Leprosy - epidemiology</topic><topic>Mycobacterium leprae</topic><topic>Mycobacterium leprae - genetics</topic><topic>on Palatine Tonsils and Adenoids of Asymptomatic Patients, Brazil</topic><topic>Palatine Tonsil</topic><topic>palatine tonsils</topic><topic>Public health</topic><topic>Research Letter</topic><topic>Surveillance</topic><topic>Tuberculosis</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Morgado de Abreu, Marilda Aparecida Milanez</creatorcontrib><creatorcontrib>Nai, Gisele Alborghetti</creatorcontrib><creatorcontrib>Molina, Juliana D'Andrea</creatorcontrib><creatorcontrib>Gomes, Rafael Tomaz</creatorcontrib><creatorcontrib>Paula, Natalia de</creatorcontrib><creatorcontrib>Roselino, Ana Maria</creatorcontrib><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>Opposing Viewpoints In Context</collection><collection>Science In Context</collection><collection>ProQuest Central (Corporate)</collection><collection>Nursing &amp; Allied Health Database</collection><collection>Health &amp; Medical Collection</collection><collection>ProQuest Central (purchase pre-March 2016)</collection><collection>Public Health Database</collection><collection>Hospital Premium Collection</collection><collection>Hospital Premium Collection (Alumni Edition)</collection><collection>ProQuest Central (Alumni) (purchase pre-March 2016)</collection><collection>ProQuest Central (Alumni)</collection><collection>ProQuest One Sustainability</collection><collection>ProQuest Central</collection><collection>ProQuest Central Essentials</collection><collection>ProQuest Central</collection><collection>ProQuest One Community College</collection><collection>Health Research Premium Collection</collection><collection>Health Research Premium Collection (Alumni)</collection><collection>Consumer Health Database (Alumni Edition)</collection><collection>ProQuest Health &amp; Medical Complete (Alumni)</collection><collection>Nursing &amp; Allied Health Database (Alumni Edition)</collection><collection>Consumer Health Database</collection><collection>Health &amp; Medical Collection (Alumni Edition)</collection><collection>Nursing &amp; Allied Health Premium</collection><collection>ProQuest One Academic Eastern Edition (DO NOT USE)</collection><collection>ProQuest One Academic</collection><collection>ProQuest One Academic UKI Edition</collection><collection>ProQuest Central China</collection><collection>MEDLINE - Academic</collection><collection>PubMed Central (Full Participant titles)</collection><collection>DOAJ Directory of Open Access Journals</collection><jtitle>Emerging infectious diseases</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Morgado de Abreu, Marilda Aparecida Milanez</au><au>Nai, Gisele Alborghetti</au><au>Molina, Juliana D'Andrea</au><au>Gomes, Rafael Tomaz</au><au>Paula, Natalia de</au><au>Roselino, Ana Maria</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Mycobacterium leprae on Palatine Tonsils and Adenoids of Asymptomatic Patients, Brazil</atitle><jtitle>Emerging infectious diseases</jtitle><addtitle>Emerg Infect Dis</addtitle><date>2020-10</date><risdate>2020</risdate><volume>26</volume><issue>10</issue><spage>2518</spage><epage>2520</epage><pages>2518-2520</pages><issn>1080-6040</issn><eissn>1080-6059</eissn><abstract>We investigated palatine tonsil and adenoid specimens excised from otorhinolaryngological patients in a leprosy-endemic region of Brazil. Fite-Faraco staining identified Mycobacterium spp. in 9 of 397 specimen blocks. Immunohistochemistry and molecular analysis confirmed the presence of Mycobacterium leprae, indicating that these organs can house M. leprae in persons inhabiting a leprosy-endemic region.</abstract><cop>United States</cop><pub>U.S. National Center for Infectious Diseases</pub><pmid>32946726</pmid><doi>10.3201/eid2610.191267</doi><tpages>3</tpages><oa>free_for_read</oa></addata></record>
fulltext fulltext
identifier ISSN: 1080-6040
ispartof Emerging infectious diseases, 2020-10, Vol.26 (10), p.2518-2520
issn 1080-6040
1080-6059
language eng
recordid cdi_doaj_primary_oai_doaj_org_article_2808684ccf96406ebfd18c0172e32696
source PubMed Central
subjects Adenoids
Antibodies
Antimicrobial agents
Asymptomatic
Brazil - epidemiology
Deoxyribonucleic acid
DNA
Drug resistance
Epidemiology
Hospitals
Humans
Immunohistochemistry
infection
Leprosy
Leprosy - epidemiology
Mycobacterium leprae
Mycobacterium leprae - genetics
on Palatine Tonsils and Adenoids of Asymptomatic Patients, Brazil
Palatine Tonsil
palatine tonsils
Public health
Research Letter
Surveillance
Tuberculosis
title Mycobacterium leprae on Palatine Tonsils and Adenoids of Asymptomatic Patients, Brazil
url http://sfxeu10.hosted.exlibrisgroup.com/loughborough?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&ctx_tim=2025-01-12T00%3A47%3A53IST&url_ver=Z39.88-2004&url_ctx_fmt=infofi/fmt:kev:mtx:ctx&rfr_id=info:sid/primo.exlibrisgroup.com:primo3-Article-gale_doaj_&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.atitle=Mycobacterium%20leprae%20on%20Palatine%20Tonsils%20and%20Adenoids%20of%20Asymptomatic%20Patients,%20Brazil&rft.jtitle=Emerging%20infectious%20diseases&rft.au=Morgado%20de%20Abreu,%20Marilda%20Aparecida%20Milanez&rft.date=2020-10&rft.volume=26&rft.issue=10&rft.spage=2518&rft.epage=2520&rft.pages=2518-2520&rft.issn=1080-6040&rft.eissn=1080-6059&rft_id=info:doi/10.3201/eid2610.191267&rft_dat=%3Cgale_doaj_%3EA638989143%3C/gale_doaj_%3E%3Cgrp_id%3Ecdi_FETCH-LOGICAL-c688t-f2f06d3e1a692c4d058fddbbf932b0e397b0de0975a4de10f144a9d9d9f5d6993%3C/grp_id%3E%3Coa%3E%3C/oa%3E%3Curl%3E%3C/url%3E&rft_id=info:oai/&rft_pqid=2466920899&rft_id=info:pmid/32946726&rft_galeid=A638989143&rfr_iscdi=true