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Cardiac complications of COVID-19: Incidence and outcomes
Coronavirus disease-2019 (COVID-19) has been associated with pre-existing cardiac conditions as well as cardiovascular complications. The incidence rates of cardiac complications, age, and gender differences in this population are unknown. We wanted to study the incidence of cardiac complications an...
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Published in: | Indian heart journal 2022-05, Vol.74 (3), p.170-177 |
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container_title | Indian heart journal |
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creator | Pillarisetti, Jayasree Cheema, Mubeen S. Haloot, Justin Panday, Manoj Badin, Auroa Mehta, Anjlee Anderson, Allen S. Prasad, Anand |
description | Coronavirus disease-2019 (COVID-19) has been associated with pre-existing cardiac conditions as well as cardiovascular complications. The incidence rates of cardiac complications, age, and gender differences in this population are unknown.
We wanted to study the incidence of cardiac complications and mortality in patients with COVID-19.
Data from the TriNetX COVID-19 global research network platform was used to identify COVID-19 patients. We compared patients with and without cardiac complications in patients with COVID-19 and obtained survival data.
The final cohort was composed of 81,844 patients with COVID-19. Cardiac complications occurred in 9.3% of patients as follows: acute coronary syndromes in 1.3%, heart failure in 4.4%, atrial fibrillation in 4.5%, sinus bradycardia 1.9%, ventricular tachycardia in 0.5% and complete heart block in 0.01%. Mortality was significantly higher in patients with the cardiac complications mentioned (20%) than in those without them (2.9%) (odds ratio 7.2, 95% CI, 6.7–7.7; p |
doi_str_mv | 10.1016/j.ihj.2022.04.008 |
format | article |
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We wanted to study the incidence of cardiac complications and mortality in patients with COVID-19.
Data from the TriNetX COVID-19 global research network platform was used to identify COVID-19 patients. We compared patients with and without cardiac complications in patients with COVID-19 and obtained survival data.
The final cohort was composed of 81,844 patients with COVID-19. Cardiac complications occurred in 9.3% of patients as follows: acute coronary syndromes in 1.3%, heart failure in 4.4%, atrial fibrillation in 4.5%, sinus bradycardia 1.9%, ventricular tachycardia in 0.5% and complete heart block in 0.01%. Mortality was significantly higher in patients with the cardiac complications mentioned (20%) than in those without them (2.9%) (odds ratio 7.2, 95% CI, 6.7–7.7; p < 0.0001). Older males seem to have higher incidence of cardiac complications and mortality.
Patients with COVID-19 who have cardiac complications have a higher risk of mortality when compared to those without cardiac complications.</description><identifier>ISSN: 0019-4832</identifier><identifier>EISSN: 2213-3763</identifier><identifier>DOI: 10.1016/j.ihj.2022.04.008</identifier><identifier>PMID: 35490848</identifier><language>eng</language><publisher>Elsevier, a division of RELX India, Pvt. Ltd</publisher><subject>Cardiac complications ; COVID-19 ; Mortality ; Original ; SARS-CoV-2</subject><ispartof>Indian heart journal, 2022-05, Vol.74 (3), p.170-177</ispartof><rights>2022 Cardiological Society of India</rights><rights>2022 Cardiological Society of India. Published by Elsevier, a division of RELX India, Pvt. Ltd. 2022 Cardiological Society of India</rights><lds50>peer_reviewed</lds50><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c517t-ac95f96296f68abef90db1ff1bb4cc69ff2d6ca7333f7bf2f03b773ff296e1343</citedby><cites>FETCH-LOGICAL-c517t-ac95f96296f68abef90db1ff1bb4cc69ff2d6ca7333f7bf2f03b773ff296e1343</cites><orcidid>0000-0002-6198-7537</orcidid></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktopdf>$$Uhttps://www.ncbi.nlm.nih.gov/pmc/articles/PMC9050189/pdf/$$EPDF$$P50$$Gpubmedcentral$$Hfree_for_read</linktopdf><linktohtml>$$Uhttps://www.sciencedirect.com/science/article/pii/S0019483222000694$$EHTML$$P50$$Gelsevier$$Hfree_for_read</linktohtml><link.rule.ids>230,314,727,780,784,885,3549,27924,27925,45780,53791,53793</link.rule.ids></links><search><creatorcontrib>Pillarisetti, Jayasree</creatorcontrib><creatorcontrib>Cheema, Mubeen S.</creatorcontrib><creatorcontrib>Haloot, Justin</creatorcontrib><creatorcontrib>Panday, Manoj</creatorcontrib><creatorcontrib>Badin, Auroa</creatorcontrib><creatorcontrib>Mehta, Anjlee</creatorcontrib><creatorcontrib>Anderson, Allen S.</creatorcontrib><creatorcontrib>Prasad, Anand</creatorcontrib><title>Cardiac complications of COVID-19: Incidence and outcomes</title><title>Indian heart journal</title><description>Coronavirus disease-2019 (COVID-19) has been associated with pre-existing cardiac conditions as well as cardiovascular complications. The incidence rates of cardiac complications, age, and gender differences in this population are unknown.
We wanted to study the incidence of cardiac complications and mortality in patients with COVID-19.
Data from the TriNetX COVID-19 global research network platform was used to identify COVID-19 patients. We compared patients with and without cardiac complications in patients with COVID-19 and obtained survival data.
The final cohort was composed of 81,844 patients with COVID-19. Cardiac complications occurred in 9.3% of patients as follows: acute coronary syndromes in 1.3%, heart failure in 4.4%, atrial fibrillation in 4.5%, sinus bradycardia 1.9%, ventricular tachycardia in 0.5% and complete heart block in 0.01%. Mortality was significantly higher in patients with the cardiac complications mentioned (20%) than in those without them (2.9%) (odds ratio 7.2, 95% CI, 6.7–7.7; p < 0.0001). Older males seem to have higher incidence of cardiac complications and mortality.
Patients with COVID-19 who have cardiac complications have a higher risk of mortality when compared to those without cardiac complications.</description><subject>Cardiac complications</subject><subject>COVID-19</subject><subject>Mortality</subject><subject>Original</subject><subject>SARS-CoV-2</subject><issn>0019-4832</issn><issn>2213-3763</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2022</creationdate><recordtype>article</recordtype><sourceid>DOA</sourceid><recordid>eNp9kc1qHDEQhEWIidd2HsC3eYGZdEsajeRAIKwTe8Hgi5Or0K-tYXe0aMaGvL213hDwJaeG6q4PuoqQS4QOAcWXsUtPY0eB0g54ByA_kBWlyFo2CPaRrABQtVwyekrO5nkEoD1X8ImcssOUXK6IWpvik3GNy7v9NjmzpDzNTY7N-v735rpFddVsJpd8mFxozOSb_LzU2zBfkJNotnP4_Heek18_fzysb9u7-5vN-vtd63ocltY41UclqBJRSGNDVOAtxojWcueEipF64czAGIuDjTQCs8PAqqxEQMbZOdkcuT6bUe9L2pnyR2eT9JuQy6M2ZUluGzSVCDQY5oUP3CKX1vcSlRSogpUeKuvbkbV_trvgXZiWYrbvoO83U3rSj_lFK-gBpaoAPAJcyfNcQvznRdCHTvSoayf60IkGrmsn1fP16Ak1pZcUip5dOsTpUwluqW-k_7hfAaLvkr0</recordid><startdate>20220501</startdate><enddate>20220501</enddate><creator>Pillarisetti, Jayasree</creator><creator>Cheema, Mubeen S.</creator><creator>Haloot, Justin</creator><creator>Panday, Manoj</creator><creator>Badin, Auroa</creator><creator>Mehta, Anjlee</creator><creator>Anderson, Allen S.</creator><creator>Prasad, Anand</creator><general>Elsevier, a division of RELX India, Pvt. Ltd</general><general>Elsevier</general><scope>6I.</scope><scope>AAFTH</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>5PM</scope><scope>DOA</scope><orcidid>https://orcid.org/0000-0002-6198-7537</orcidid></search><sort><creationdate>20220501</creationdate><title>Cardiac complications of COVID-19: Incidence and outcomes</title><author>Pillarisetti, Jayasree ; Cheema, Mubeen S. ; Haloot, Justin ; Panday, Manoj ; Badin, Auroa ; Mehta, Anjlee ; Anderson, Allen S. ; Prasad, Anand</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c517t-ac95f96296f68abef90db1ff1bb4cc69ff2d6ca7333f7bf2f03b773ff296e1343</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2022</creationdate><topic>Cardiac complications</topic><topic>COVID-19</topic><topic>Mortality</topic><topic>Original</topic><topic>SARS-CoV-2</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Pillarisetti, Jayasree</creatorcontrib><creatorcontrib>Cheema, Mubeen S.</creatorcontrib><creatorcontrib>Haloot, Justin</creatorcontrib><creatorcontrib>Panday, Manoj</creatorcontrib><creatorcontrib>Badin, Auroa</creatorcontrib><creatorcontrib>Mehta, Anjlee</creatorcontrib><creatorcontrib>Anderson, Allen S.</creatorcontrib><creatorcontrib>Prasad, Anand</creatorcontrib><collection>ScienceDirect Open Access Titles</collection><collection>Elsevier:ScienceDirect:Open Access</collection><collection>CrossRef</collection><collection>PubMed Central (Full Participant titles)</collection><collection>DOAJ Directory of Open Access Journals</collection><jtitle>Indian heart journal</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Pillarisetti, Jayasree</au><au>Cheema, Mubeen S.</au><au>Haloot, Justin</au><au>Panday, Manoj</au><au>Badin, Auroa</au><au>Mehta, Anjlee</au><au>Anderson, Allen S.</au><au>Prasad, Anand</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Cardiac complications of COVID-19: Incidence and outcomes</atitle><jtitle>Indian heart journal</jtitle><date>2022-05-01</date><risdate>2022</risdate><volume>74</volume><issue>3</issue><spage>170</spage><epage>177</epage><pages>170-177</pages><issn>0019-4832</issn><eissn>2213-3763</eissn><abstract>Coronavirus disease-2019 (COVID-19) has been associated with pre-existing cardiac conditions as well as cardiovascular complications. The incidence rates of cardiac complications, age, and gender differences in this population are unknown.
We wanted to study the incidence of cardiac complications and mortality in patients with COVID-19.
Data from the TriNetX COVID-19 global research network platform was used to identify COVID-19 patients. We compared patients with and without cardiac complications in patients with COVID-19 and obtained survival data.
The final cohort was composed of 81,844 patients with COVID-19. Cardiac complications occurred in 9.3% of patients as follows: acute coronary syndromes in 1.3%, heart failure in 4.4%, atrial fibrillation in 4.5%, sinus bradycardia 1.9%, ventricular tachycardia in 0.5% and complete heart block in 0.01%. Mortality was significantly higher in patients with the cardiac complications mentioned (20%) than in those without them (2.9%) (odds ratio 7.2, 95% CI, 6.7–7.7; p < 0.0001). Older males seem to have higher incidence of cardiac complications and mortality.
Patients with COVID-19 who have cardiac complications have a higher risk of mortality when compared to those without cardiac complications.</abstract><pub>Elsevier, a division of RELX India, Pvt. Ltd</pub><pmid>35490848</pmid><doi>10.1016/j.ihj.2022.04.008</doi><tpages>8</tpages><orcidid>https://orcid.org/0000-0002-6198-7537</orcidid><oa>free_for_read</oa></addata></record> |
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subjects | Cardiac complications COVID-19 Mortality Original SARS-CoV-2 |
title | Cardiac complications of COVID-19: Incidence and outcomes |
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