Long-Term Clinical and Safety Outcomes of Canaloplasty Performed across All Grades of Glaucoma Severity

• Published in: Journal of ophthalmology 2023-05, Vol.2023 (1), p.5625990
• Main Authors: Patel, Shamil, Reiss, George
• Format: Article
• Language: English
• Subjects: Cataract; Comparative analysis; Glaucoma; Ophthalmic drugs; Patient compliance; Safety and security measures; Surgery
• ISSN: 2090-004X; 2090-0058
• DOI: 10.1155/2023/5625990

Purpose. To investigate the clinical effectiveness of canaloplasty performed with an ab interno technique using the iTrack microcatheter (Nova Eye Medical) in patients with mild-moderate glaucoma as compared to severe glaucoma. Methods. This is a retrospective single-center case series. Patients were preoperatively categorized as mild/moderate vs. severe glaucoma assessed using the mean deviation (MD) score and controlled group (baseline intraocular pressure (IOP) ≤18 mmHg) vs. uncontrolled group (>18 mmHg). All patients with glaucoma were eligible for recruitment except those who had undergone previous glaucoma surgery (with the exception of selective laser trabeculoplasty or SLT). Patients underwent canaloplasty via an ab interno surgical technique with or without phacoemulsification and were monitored for IOP, glaucoma medication usage, and surgical complications. Results. In total, 72 eyes were followed for 3.4 ± 0.5 years. Mean pre-op IOP (mmHg) was 19.3 ± 7.7 in the standalone group (n = 9) and 18.5 ± 5.6 in the combined group (n = 63) (p=0.38). At the last follow-up, mean IOP reduced by 36% to 12.4 ± 4.4 (p=0.02) in the standalone group and by 26% to 13.7 ± 4.8 in the combined group (p