Stimulants associated with reduced risk of hospitalization for motor vehicle accident injury in patients with obstructive sleep apnea-a nationwide cohort study

• Published in: BMC pulmonary medicine 2020-02, Vol.20 (1), p.28-28, Article 28
• Main Authors: Lin, Yi-Chang, Chen, Tien-Yu, Chien, Wu-Chien, Chung, Chi-Hsiang, Chang, Hsin-An, Kao, Yu-Chen, Tsai, Chien-Sung, Lin, Chih-Sheng, Tzeng, Nian-Shen
• Format: Article
• Language: English
• Subjects: Apnea; Care and treatment; Cohort analysis; Cohort study; Complications and side effects; Crash injuries; Demographic aspects; Health; Health aspects; Health insurance; Hospitalization; Longitudinal health insurance database; Medical research; Methylphenidate; Modafinil; Motor vehicle accident injury; National health insurance; National Health Insurance Research Database; Obstructive sleep apnea; Online databases; Psychotropic drugs; Pulmonology; Sleep; Sleep apnea; Sleep disorders; Stimulants; Studies; Traffic accidents; Traffic accidents & safety
• ISSN: 1471-2466; 1471-2466
• DOI: 10.1186/s12890-019-1041-1

The risk of injury directly related to hospitalization for motor vehicle accidents (MVAs) in the obstructive sleep apnea (OSA) patients has not been thoroughly understood. Our study aimed to examine the association between the OSA and the hospitalization for an MVA injury. This retrospective cohort study used Taiwan's National Health Insurance Research Database (NHIRD) between 2000 and 2015. The OSA patients aged ≥20 years by age, sex, and index-year matched by non-OSA controls were enrolled (1:3). We used the Cox proportional regression model to evaluate the association between the OSA and the hospitalization for an MVA injury. The incidence rate of hospitalization for an MVA injury was higher in the OSA cohort (N = 3025) when compared with the non-OSA controls (N = 9075), as 575.3 and 372.0 per 100,000 person-years, respectively (p