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Distinct cardiovascular and cancer burdens associated with social position, work environment and unemployment: a cross-sectional and retrospective study in a large population-based French cohort

ObjectivesDistinguish the respective effects of social position, work environment and unemployment on cardiovascular and cancer risks.DesignA cross-sectional and retrospective observational study.SettingA population-based French cohort (CONSTANCES).Participants130 197 adults enrolled between 2012 an...

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Bibliographic Details
Published in:BMJ open 2023-07, Vol.13 (7), p.e074835-e074835
Main Authors: Sanchez Rico, Marina, Plessz, Marie, Airagnes, Guillaume, Ribet, Céline, Hoertel, Nicolas, Goldberg, Marcel, Zins, Marie, Meneton, Pierre
Format: Article
Language:English
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Summary:ObjectivesDistinguish the respective effects of social position, work environment and unemployment on cardiovascular and cancer risks.DesignA cross-sectional and retrospective observational study.SettingA population-based French cohort (CONSTANCES).Participants130 197 adults enrolled between 2012 and 2021 without missing values.Primary outcome measuresThe associations of social position, work environment and unemployment exposure with the prevalence of cardiovascular events and cancers simultaneously tested using logistic regression models adjusting for common risk factors.ResultsWhile social position, work environment and unemployment exposure are strongly inter-related with each other, they are not linked to the same cardiovascular and cancer outcomes. Low social position and long unemployment duration are significantly associated with an increased prevalence of angina pectoris, myocardial infarction and peripheral arterial disease (OR=1.22 to 1.90, p
ISSN:2044-6055
2044-6055
DOI:10.1136/bmjopen-2023-074835