Fatal intestinal basidiobolomycosis in a pediatric patient

Basidiobolomycosis is a rare but emerging fungal infection that causes severe and occasionally fatal illness. We present the case of a child with an abdominal mass and leukocytosis at the expense of eosinophilia, who underwent exploratory laparotomy showing a mass involving the transverse colon and...

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Bibliographic Details
Published in:Journal of pediatric surgery case reports 2022-06, Vol.81, p.102224, Article 102224
Main Authors: Fernandez, Pamela, Vidales-Nieto, Esperanza
Format: Article
Language:English
Subjects:
Basidiobolomycosis
Gastrointestinal
Itraconazole
Pediatrics
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Summary:Basidiobolomycosis is a rare but emerging fungal infection that causes severe and occasionally fatal illness. We present the case of a child with an abdominal mass and leukocytosis at the expense of eosinophilia, who underwent exploratory laparotomy showing a mass involving the transverse colon and ileum. With histopathological report of hyphae with few septa, highlighted by PAS and Grocott stains and surrounded by eosinophilic and hyaline material (Splendore-Höeppli phenomenon). Treatment with amphotericin B was started, however, he presented jejunal anastomosis dehiscence, with poor evolution, for which he died days later.
ISSN:2213-5766
2213-5766
DOI:10.1016/j.epsc.2022.102224