Comparative genomics reveals a widespread distribution of an exopolysaccharide biosynthesis gene cluster among Vibrionaceae

The eps locus in Vibrio diabolicus is involved in the production of the biotechnologically valuable HE800 EPS. In this study, the distribution and diversity of similar eps gene clusters across Vibrionaceae and its variability in relation to phylogenetic relationship were investigated. The aim was to...

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Bibliographic Details
Published in:BMC research notes 2018-02, Vol.11 (1), p.102-102, Article 102
Main Authors: Lebellenger, Lou, Verrez-Bagnis, Véronique, Passerini, Delphine, Delbarre-Ladrat, Christine
Format: Article
Language:English
Subjects:
Biofilms
Biosynthesis
Comparative analysis
Divergence
Eps gene
Exopolysaccharide
Exopolysaccharides
Gene clusters
Genes
Genetic aspects
Genetic biodiversity
Genomes
Genomics
Glycosyltransferase
Gram-negative bacteria
HE800 EPS
Kinases
Life Sciences
Marine bacteria
Phylogenetics
Phylogeny
Proteins
Research Note
Speciation
Synteny
Vertical transfer
Vibrio diabolicus
Vibrionaceae
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Summary:The eps locus in Vibrio diabolicus is involved in the production of the biotechnologically valuable HE800 EPS. In this study, the distribution and diversity of similar eps gene clusters across Vibrionaceae and its variability in relation to phylogenetic relationship were investigated. The aim was to provide a better knowledge of the eps gene cluster importance and to facilitate discovery of new EPS with potent interesting bioactivities. Seventy percent of the 103 genome sequences examined display such an eps locus with a high level of synteny. However, genetic divergence was found inside some monophyletic clades or even between some strains of the same species. It includes gene insertions, truncations, and deletions. Comparative analysis also reveals some variations in glycosyltransferase and export systems genes. Phylogenetic analysis of the Vibrionaceae eps gene clusters within Vibrionaceae suggests a vertical transfer by speciation but also pinpoints rearrangement events independent of the speciation.
ISSN:1756-0500
1756-0500
DOI:10.1186/s13104-018-3214-z