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Granular cell tumor in breast: a case report

Granular cell tumor (GCT) is a rare neoplasm of the soft tissues, and

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Published in:Breast cancer targets and therapy 2017-01, Vol.9, p.245-248
Main Authors: Castillo Lara, Maria, Martínez Herrera, Antonia, Torrejón Cardoso, Rafael, Lubián López, Daniel Maria
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container_title Breast cancer targets and therapy
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creator Castillo Lara, Maria
Martínez Herrera, Antonia
Torrejón Cardoso, Rafael
Lubián López, Daniel Maria
description Granular cell tumor (GCT) is a rare neoplasm of the soft tissues, and
doi_str_mv 10.2147/BCTT.S131446
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It usually appears in the tongue and sometimes may affect the female breast. Initially, GCT was considered to be a myogenic lesion affecting female breast (myoblastoma). Actually, it is assumed as a tumor originating from perineural or putative Schwann cells of peripheral nerves or their precursors that grows in the lobular breast tissue, due to the immunohistochemical features. Here, we review the importance of differentiating between this tumor and malignant breast carcinoma. Mammographically, by ultrasound scan and clinically, this case appears to be a malignant tumor of the breast, but with a correct and precise diagnosis including histopathologic examination and immunohistochemical studies, it was correctly identified as a GCT. We present a case of a 52-year-old premenopausal woman. This report is of interest because of patient's familial oncologic history and personal history of gynecologic cancer. This rare tumor of the breast and the special way to approach the tumor by local anesthesia makes it interesting to communicate. This is a case of interest because GCT located in the breast is very unusual and knowledge of GCT is required for the differential diagnosis with breast cancer.</description><identifier>ISSN: 1179-1314</identifier><identifier>EISSN: 1179-1314</identifier><identifier>DOI: 10.2147/BCTT.S131446</identifier><identifier>PMID: 28442932</identifier><language>eng</language><publisher>New Zealand: Dove Medical Press Limited</publisher><subject>Biopsy ; Breast ; Breast cancer ; Calretinin ; Carcinoma ; Care and treatment ; Case Report ; Case reports ; Case studies ; Diagnosis ; Females ; Local anesthesia ; Mammography ; Neoplasia ; Nervous system ; PAS diastase ; Pathology ; Proteins ; S-protein ; Tumors ; Ultrasonic imaging</subject><ispartof>Breast cancer targets and therapy, 2017-01, Vol.9, p.245-248</ispartof><rights>COPYRIGHT 2017 Dove Medical Press Limited</rights><rights>2017. This work is licensed under https://creativecommons.org/licenses/by-nc/3.0/ (the “License”). 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subjects Biopsy
Breast
Breast cancer
Calretinin
Carcinoma
Care and treatment
Case Report
Case reports
Case studies
Diagnosis
Females
Local anesthesia
Mammography
Neoplasia
Nervous system
PAS diastase
Pathology
Proteins
S-protein
Tumors
Ultrasonic imaging
title Granular cell tumor in breast: a case report
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