Clinical and epidemiological aspects of microcephaly in the state of Piauí, northeastern Brazil, 2015–2016

To describe aspects of the microcephaly epidemic in the state of Piauí. All cases of congenital microcephaly confirmed in the state between 2015 and 2016 were included (n=100). Investigation forms of the Regional Reference Center for Microcephaly were reviewed. Discarded cases (n=63) were used as a...

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Bibliographic Details
Published in:Jornal de pediatria 2019-07, Vol.95 (4), p.466-474
Main Authors: Almeida, Isabel Marlúcia Lopes Moreira de, Ramos, Carmen Viana, Rodrigues, Danielle Carvalho, Sousa, Amanda Carvalho de, Nascimento, Maria de Lourdes Cristina Alcântara Paz Carvalho do, Silva, Marcos Vilhena Bittencourt da, Batista, Francisca Miriane Araújo, Santos, Jéssica Pereira dos, Oliveira, Roselane Sampaio de, Soares, Filipe Augusto de Freitas, Xavier, Samanta Cristina das Chagas, Carvalho-Costa, Filipe Anibal
Format: Article
Language:English
Subjects:
Adolescent
Adult
Brazil - epidemiology
Cephalometry
Disease Outbreaks
Estado do Piauí
Female
Gestational Age
Humans
Incidence
Infants
Microcefalia
Microcephaly
Microcephaly - diagnosis
Microcephaly - epidemiology
Microcephaly - virology
Neonatos
Pregnancy
Pregnancy Complications, Infectious - epidemiology
Pregnancy Complications, Infectious - virology
Residence Characteristics
Spatio-Temporal Analysis
State of Piauí
Young Adult
Zika
Zika Virus - isolation & purification
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Summary:To describe aspects of the microcephaly epidemic in the state of Piauí. All cases of congenital microcephaly confirmed in the state between 2015 and 2016 were included (n=100). Investigation forms of the Regional Reference Center for Microcephaly were reviewed. Discarded cases (n=63) were used as a comparison group. In October, November, and December 2015 incidence rates reached 4.46, 6.33 and 3.86/1000 live births, respectively; 44 cases were reported in the state capital. Among the mothers of confirmed and discarded cases, the frequency of skin rash during pregnancy was 50/97 (51.5%) and 8/51 (15.7%), respectively (p
ISSN:0021-7557
1678-4782
DOI:10.1016/j.jped.2018.04.013