Choroidal neovascularization associated with combined hamartoma of retina and retinal pigment epithelium: Multimodal imaging

Combined hamartoma of retina and retinal pigment epithelium (CHRRPE) has been considered as a congenital benign entity with evidence of choroidal neovascularization membranes (CNVM) being associated with it in literature. This case series gives insight into the pathogenesis and the predisposing fact...

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Bibliographic Details
Published in:Indian journal of ophthalmology 2018-12, Vol.66 (12), p.1866-1868
Main Authors: Gupta, Rajan, Pappuru, Rajeev, Dave, Vivek, Chhablani, Jay
Format: Article
Language:English
Subjects:
Angiography
Bridge Sign
Case Reports
choroidal neovascularization associated with combined hamartoma of retina and retinal pigment epithelium
combined hamartoma of retina and retinal pigment epithelium
Epithelium
Hemorrhage
Medical imaging
Neoplasia
OCTA in CHRRPE
Ophthalmology
Retina
Retinal pigment epithelium
Tomography
Vascular endothelial growth factor
Vascularization
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Description
Summary:Combined hamartoma of retina and retinal pigment epithelium (CHRRPE) has been considered as a congenital benign entity with evidence of choroidal neovascularization membranes (CNVM) being associated with it in literature. This case series gives insight into the pathogenesis and the predisposing factors leading to CNVM formation in peripapillary CHRRPE using swept-source optical coherence tomography. In addition, lack of typical markers of CNVM (subretinal fluid/pigment epithelial detachment) in CHRRPE highlights the utility of optical coherence tomography angiography and the subtle optical coherence tomography findings such as "Bridge Sign" that could be instrumental in early diagnosis of CNVM in CHRRPE.
ISSN:0301-4738
1998-3689
DOI:10.4103/ijo.IJO_992_18