Delineating meta-quantitative trait loci for anthracnose resistance in common bean ( Phaseolus vulgaris L.)

Anthracnose, caused by the fungus , is one of the devastating disease affecting common bean production and productivity worldwide. Several quantitative trait loci (QTLs) for anthracnose resistance have been identified. In order to make use of these QTLs in common bean breeding programs, a detailed m...

Full description

Saved in:
Bibliographic Details
Published in:Frontiers in plant science 2022-08, Vol.13, p.966339
Main Authors: Shafi, Safoora, Saini, Dinesh Kumar, Khan, Mohd Anwar, Bawa, Vanya, Choudhary, Neeraj, Dar, Waseem Ali, Pandey, Arun K, Varshney, Rajeev Kumar, Mir, Reyazul Rouf
Format: Article
Language:English
Subjects:
anthracnose
candidate genes
common beans
GWAS
meta-QTL
Plant Science
QTL
Citations: Items that this one cites
Online Access:Get full text
Tags: Add Tag
No Tags, Be the first to tag this record!
Description
Summary:Anthracnose, caused by the fungus , is one of the devastating disease affecting common bean production and productivity worldwide. Several quantitative trait loci (QTLs) for anthracnose resistance have been identified. In order to make use of these QTLs in common bean breeding programs, a detailed meta-QTL (MQTL) analysis has been conducted. For the MQTL analysis, 92 QTLs related to anthracnose disease reported in 18 different earlier studies involving 16 mapping populations were compiled and projected on to the consensus map. This meta-analysis led to the identification of 11 MQTLs (each involving QTLs from at least two different studies) on 06 bean chromosomes and 10 QTL hotspots each involving multiple QTLs from an individual study on 07 chromosomes. The confidence interval (CI) of the identified MQTLs was found 3.51 times lower than the CI of initial QTLs. Marker-trait associations (MTAs) reported in published genome-wide association studies (GWAS) were used to validate nine of the 11 identified MQTLs, with MQTL4.1 overlapping with as many as 40 MTAs. Functional annotation of the 11 MQTL regions revealed 1,251 genes including several R genes (such as those encoding for NBS-LRR domain-containing proteins, protein kinases, etc.) and other defense related genes. The MQTLs, QTL hotspots and the potential candidate genes identified during the present study will prove useful in common bean marker-assisted breeding programs and in basic studies involving fine mapping and cloning of genomic regions associated with anthracnose resistance in common beans.
ISSN:1664-462X
1664-462X
DOI:10.3389/fpls.2022.966339