Relationship between adiponectin and blood pressure in obese Latino adolescent boys with a family history of type 2 diabetes

Adipokines are associated with several pathological states including, metabolic syndrome, obesity, insulin resistance and type 2 diabetes. One of these adipokines, adiponectin is of particular interest as it has been shown to have numerous anti-inflammatory effects, However, the association between...

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Bibliographic Details
Published in:BMC pediatrics 2023-10, Vol.23 (1), p.523-523, Article 523
Main Authors: Hijazin, Kristin, Smith, Brandon, Garrett, Coleby, Knox, Allan, Kelly, Louise A
Format: Article
Language:English
Subjects:
Adipokines
Adiponectin
Adiponectin - blood
Adolescent
Adults
Age
Analysis
Blood Pressure
Body Mass Index
Boys
Children & youth
Demographic aspects
Development and progression
Diabetes
Diabetes Mellitus, Type 2
Disease
Families & family life
Family medical history
Genetic aspects
Glucose
Health aspects
Hispanic Americans
Hispanic or Latino
Humans
Hypertension
Insulin Resistance
Latino youth
Male
Males
Metabolic syndrome
Minority & ethnic groups
Obesity
Obesity in adolescence
Pediatric
Pediatric Obesity
Pediatrics
Plasma
Proteins
Regression analysis
Teenagers
Type 2 diabetes
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Summary:Adipokines are associated with several pathological states including, metabolic syndrome, obesity, insulin resistance and type 2 diabetes. One of these adipokines, adiponectin is of particular interest as it has been shown to have numerous anti-inflammatory effects, However, the association between adiponectin and blood pressure remains inconclusive especially in the Latino adolescent with obesity. To investigate the relationship between plasma adiponectin and blood pressure in Latino adolescents' boys with obesity and a with a family history of Type 2 diabetes. Thirty two Latino adolescent males with obesity aged 14-17 years with a family history of type 2 diabetes underwent a frequently sampled glucose tolerance test (FSIVGTT) to measure insulin sensitivity. Body composition was assessed using dual energy x-ray absorptiometry. Obesity was defined as having a BMI percentile ≥95. Blood pressure was assessed using the Dinamap automated blood pressure monitor, and the average of three readings was used in the analysis. Fasting plasma adiponectin was determined using radioimmunoassay. There were moderate positive significant correlations for adiponectin and Systolic blood pressure(SBP) (rho = 0.436, p 
ISSN:1471-2431
1471-2431
DOI:10.1186/s12887-023-04337-y