One-Step Surface Functionalized Hydrophilic Polypropylene Meshes for Hernia Repair Using Bio-Inspired Polydopamine

An ideal hernia mesh is one that absorbs drugs and withstands muscle forces after mesh implantation. Polypropylene (PP) mesh devices have been accepted as a standard material to repair abdominal hernia, but the hydrophobicity of PP fibers makes them unsuitable to carry drugs during the pre-implantat...

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Bibliographic Details
Published in:Fibers 2019-01, Vol.7 (1), p.6
Main Authors: Sanbhal, Noor, Saitaer, Xiakeer, Peerzada, Mazhar, Habboush, Ali, Wang, Fujun, Wang, Lu
Format: Article
Language:English
Subjects:
Contact angle
Dopamine
Drugs
Electron microscopes
Fourier transforms
hernia meshes
Hernias
Hydrophilicity
Hydrophobicity
Implantation
Infections
Infrared imagery
Medical equipment
Morphology
Muscles
polydopamine
Polyethylene terephthalate
Polymerization
Polypropylene
Spectrum analysis
surface functionalization
Variance analysis
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Summary:An ideal hernia mesh is one that absorbs drugs and withstands muscle forces after mesh implantation. Polypropylene (PP) mesh devices have been accepted as a standard material to repair abdominal hernia, but the hydrophobicity of PP fibers makes them unsuitable to carry drugs during the pre-implantation of PP meshes. In this study, for the first time, one-step functionalization of PP mesh surfaces was performed to incorporate bio-inspired polydopamine (PDA) onto PP surfaces. All PP mesh samples were dipped in the same concentration of dopamine solution. The surface functionalization of PP meshes was performed for 24 h at 37 °C and 80 rpm. It was proved by scanning electron microscopic (SEM) images and Fourier Transform Infrared Spectroscopy (FTIR) results that a thin layer of PDA was connected with PP surfaces. Moreover, water contact angle results proved that surface functionalized PP meshes were highly hydrophilic (73.1°) in comparison to untreated PP mesh surfaces (138.5°). Thus, hydrophilic PP meshes with bio-inspired poly-dopamine functionalization could be a good choice for hernia mesh implantation.
ISSN:2079-6439
2079-6439
DOI:10.3390/fib7010006