Rat-to-human transmission of Cowpox infection

We isolated Cowpox virus (CPXV) from the ulcerative eyelid lesions of a 14-year-old girl, who had cared for a clinically ill wild rat that later died. CPXV isolated from the rat (Rattus norvegicus) showed complete homology with the girl's virus. Our case is the first proven rat-to-human transmi...

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Bibliographic Details
Published in:Emerging infectious diseases 2002-12, Vol.8 (12), p.1495-1496
Main Authors: Wolfs, Tom F W, Wagenaar, Jaap A, Niesters, Hubert G M, Osterhaus, Albert D M E
Format: Article
Language:English
Subjects:
Adolescent
Animals
Communicable diseases
Cowpox
Cowpox - transmission
Cowpox virus
Cowpox virus - isolation & purification
Cowpox virus - pathogenicity
Disease transmission
Dispatch
Female
Health aspects
Humans
Rats
Rattus norvegicus
Rodents
the Netherlands
transmission
zoonosis
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Summary:We isolated Cowpox virus (CPXV) from the ulcerative eyelid lesions of a 14-year-old girl, who had cared for a clinically ill wild rat that later died. CPXV isolated from the rat (Rattus norvegicus) showed complete homology with the girl's virus. Our case is the first proven rat-to-human transmission of cowpox.
ISSN:1080-6040
1080-6059
DOI:10.3201/eid0812.020089