Quality of life in keratoconus: evaluation with Keratoconus Outcomes Research Questionnaire (KORQ)

To assess the quality of life of keratoconus patients using the Keratoconus Outcomes Research Questionnaire (KORQ), translated and validated in Portuguese language. The KORQ is the only validated keratoconus specific questionnaire and has a high rating for its psychometric properties. This cross-sec...

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Bibliographic Details
Published in:Scientific reports 2021-06, Vol.11 (1), p.12970-12970, Article 12970
Main Authors: Pinto, Roberto Damian Pacheco, Abe, Ricardo Yuji, Gomes, Flávia Cid, Barbisan, Paulo Rodolfo Tagliari, Martini, Alexandre Fattah, de Almeida Borges, Daniel, Fernandes, Arthur Gustavo, Arieta, Carlos Eduardo Leite, Alves, Monica
Format: Article
Language:English
Subjects:
692/1807/1482
692/699/3161/3163
692/700/784
Acuity
Adolescent
Adult
Comorbidity
Conjunctivitis
Corneal Topography
Eye
Female
Hay fever
Humanities and Social Sciences
Humans
Keratoconus
Keratoconus - diagnosis
Keratoconus - epidemiology
Male
Middle Aged
multidisciplinary
Multivariate analysis
Outcome Assessment, Health Care
Patients
Public Health Surveillance
Quality of Life
Questionnaires
Science
Science (multidisciplinary)
Severity of Illness Index
Surveys and Questionnaires
Symptom Assessment
Visual Acuity
Young Adult
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Summary:To assess the quality of life of keratoconus patients using the Keratoconus Outcomes Research Questionnaire (KORQ), translated and validated in Portuguese language. The KORQ is the only validated keratoconus specific questionnaire and has a high rating for its psychometric properties. This cross-sectional study enrolled 100 keratoconus patients from a tertiary referral eye hospital between April 2018 and June 2019. Associations between age, sex, allergic conjunctivitis, keratoconus stage, best-corrected visual acuity (BCVA), maximum simulated keratometry (Kmax), steep keratometry (K2), pachymetry, treatments performed, hydrops, and KORQ scores were evaluated using univariate (Wilcoxon test and the Kruskal Wallis test) and multivariate linear regression with stepwise backward modeling. Lower KORQ scores are associated with better quality of life, whereas, higher scores are associated with greater impairment of functional activities and symptoms. Among the 100 patients, mild, moderate, and severe keratoconus were observed in 15%, 46% and 39% of participants, respectively. Univariate analysis showed lower function scores values, with male sex ( p  
ISSN:2045-2322
2045-2322
DOI:10.1038/s41598-021-92346-1