Infant study of hemispheric asymmetry after long‐gap esophageal atresia repair

Objectives Previous studies have demonstrated that infants are typically born with a left‐greater‐than‐right forebrain asymmetry that reverses throughout the first year of life. We hypothesized that critically ill term‐born and premature patients following surgical and critical care for long‐gap eso...

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Bibliographic Details
Published in:Annals of clinical and translational neurology 2021-11, Vol.8 (11), p.2132-2145
Main Authors: Kagan, Mackenzie S., Mongerson, Chandler R. L., Zurakowski, David, Jennings, Russell W., Bajic, Dusica
Format: Article
Language:English
Subjects:
Anesthesia
Asymmetry
Brain research
Congenital diseases
Critical care
Esophageal Atresia - pathology
Esophageal Atresia - surgery
Esophagus
Extracorporeal membrane oxygenation
Female
Fistula
Gestational age
Humans
Infant
Magnetic Resonance Imaging
Male
Pilot Projects
Premature babies
Premature birth
Prosencephalon - anatomy & histology
Prosencephalon - diagnostic imaging
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Summary:Objectives Previous studies have demonstrated that infants are typically born with a left‐greater‐than‐right forebrain asymmetry that reverses throughout the first year of life. We hypothesized that critically ill term‐born and premature patients following surgical and critical care for long‐gap esophageal atresia (LGEA) would exhibit alteration in expected forebrain asymmetry. Methods Term‐born (n = 13) and premature (n = 13) patients, and term‐born controls (n = 23)
ISSN:2328-9503
2328-9503
DOI:10.1002/acn3.51465