Flupirtine: Clinical pharmacology

Flupirtine is neither an opioid nor a non steroidal anti-inflammatory drug (NSAID) producing its analgesic action through blockade of glutamate N-methyl-D-aspartate receptor. It is devoid of adverse effects of routinely used analgesic drugs, but is equally efficacious in reducing pain sensation. It...

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Bibliographic Details
Published in:Journal of anaesthesiology, clinical pharmacology clinical pharmacology, 2012-04, Vol.28 (2), p.172-177
Main Authors: Harish, S, Bhuvana, K, Bengalorkar, Girish M, Kumar, Tn
Format: Article
Language:English
Subjects:
Aminopyridines
Care and treatment
Clinical Pharmacology
Flupirtine
N-methyl-D-aspartate receptor
non-steroidal anti-inflammatory drug
opioids
Pain
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Summary:Flupirtine is neither an opioid nor a non steroidal anti-inflammatory drug (NSAID) producing its analgesic action through blockade of glutamate N-methyl-D-aspartate receptor. It is devoid of adverse effects of routinely used analgesic drugs, but is equally efficacious in reducing pain sensation. It has a distinctive mechanism of action, exerting a dual therapeutic effect with both analgesic and muscle relaxant properties that has utility in the treatment of pain, including that associated with muscle tension.
ISSN:0970-9185
2231-2730
DOI:10.4103/0970-9185.94833