Large intraperitoneal lipoleiomyoma in a pre-menopausal woman: a case report

Lipoleiomyoma is a rare, benign variant of the commonplace uterine leiomyoma. Unlike leiomyoma, these tumors are composed of smooth muscle cells admixed with mature adipose tissue. While rare, they are most frequently identified in the uterus, but even more infrequently have been described in extrau...

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Bibliographic Details
Published in:World journal of surgical oncology 2021-05, Vol.19 (1), p.144-144, Article 144
Main Authors: Schaefer, Sara L, Strong, Amy L, Bahroloomi, Sheena, Han, Jichang, Whisman, Michella K, Wilkowski, Jodi M, Angeles, Christina V
Format: Article
Language:English
Subjects:
Abdomen
Actin
Adipose tissue
Benign
Biopsy
Care and treatment
Case Report
Case studies
Desmin
Diagnosis
Differential diagnosis
Estrogen receptors
Estrogens
Female
Fibroids
Humans
In vitro fertilization
Leiomyoma
Leiomyoma - diagnostic imaging
Leiomyoma - surgery
Lipoleiomyoma
Lipoma
Liposarcoma
Magnetic resonance imaging
Malignancy
Menopause
Mesentery
Metastasis
Middle Aged
Muscles
Myolipoma of soft tissue
Pathogenesis
Patients
Pre-menopausal
Pregnancy
Premenopause
Prognosis
Sarcoma
Smooth muscle
Surgery
Surveillance
Tumors
Uterine Neoplasms
Uterus
Weight loss
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Summary:Lipoleiomyoma is a rare, benign variant of the commonplace uterine leiomyoma. Unlike leiomyoma, these tumors are composed of smooth muscle cells admixed with mature adipose tissue. While rare, they are most frequently identified in the uterus, but even more infrequently have been described in extrauterine locations. We describe a case report of a 45-year-old woman with a history of in vitro fertilization pregnancy presenting 6 years later with abdominal distention and weight loss found to have a 30-cm intra-abdominal lipoleiomyoma. While cross-sectional imaging can narrow the differential diagnosis, histopathological analysis with stains positive for smooth muscle actin, desmin, and estrogen receptor, but negative for HMB-45 confirms the diagnosis of lipoleiomyoma. The large encapsulated tumor was resected en bloc. The patients post-operative course was uneventful and her symptoms resolved. Lipoleiomyoma should be considered on the differential diagnosis in a woman with a large intra-abdominal mass. While considered benign, resection should be considered if the mass is symptomatic, and the diagnosis is unclear or there is a concern for malignancy.
ISSN:1477-7819
1477-7819
DOI:10.1186/s12957-021-02256-9