Syringocystadenocarcinoma Papilliferum in a Fifteen-Year-Old Girl: A Case Report and Review of the Literature

Syringocystadenocarcinoma papilliferum (SCACP) is a rare malignant neoplasm arising from adnexal tissues and is the malignant complement to the benign neoplasm syringocystadenoma papilliferum (SCAP). SCACP lesions appear as raised nodules or inflammatory plaques and can be associated with SCAP or ne...

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Bibliographic Details
Published in:Case reports in dermatological medicine 2022-02, Vol.2022, p.8076649-5
Main Authors: Halsey, Jordan N., Faith, Esteban Fernandez, Logan, Suzanna J., Shenoy, Archana, Schieffer, Kathleen M., Cottrell, Catherine E., Lillis, Anna P., Aldrink, Jennifer H., Setty, Bhuvana A., Pearson, Gregory D.
Format: Article
Language:English
Subjects:
Amino acids
Case Report
Case reports
Dermatology
Gene expression
Kinases
Lymphatic system
Magnetic resonance imaging
Metastasis
Patients
Pediatrics
Skin cancer
Surveillance
Teenage girls
Teenagers
Tumors
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Description
Summary:Syringocystadenocarcinoma papilliferum (SCACP) is a rare malignant neoplasm arising from adnexal tissues and is the malignant complement to the benign neoplasm syringocystadenoma papilliferum (SCAP). SCACP lesions appear as raised nodules or inflammatory plaques and can be associated with SCAP or nevus sebaceous. There have been fewer than 100 described cases of this neoplasm in the literature, and all previously published cases have been described in adults, with the majority occurring in the elderly. We present a case of an adolescent female with a syringocystadenocarcinoma papilliferum arising from a large thigh mass harboring an in-frame alteration in MAP2K1 along with a brief review of the literature.
ISSN:2090-6463
2090-6471
DOI:10.1155/2022/8076649