Mild traumatic brain injury, PTSD symptom severity, and behavioral dyscontrol: a LIMBIC-CENC study

• Published in: Frontiers in neurology 2023, Vol.14, p.1286961
• Main Authors: Stromberg, Kelsee M, Martindale, Sarah L, Walker, William C, Ou, Zhining, Pogoda, Terri K, Miles, Shannon R, Dismuke-Greer, Clara E, Carlson, Kathleen F, Rowland, Jared A, O'Neil, Maya E, Pugh, Mary Jo
• Format: Article
• Language: English
• Subjects: concussion; dysregulation; military members; Neurology; TBI – traumatic brain injury; transition introduction
• ISSN: 1664-2295; 1664-2295
• DOI: 10.3389/fneur.2023.1286961

Behavioral dyscontrol occurs commonly in the general population and in United States service members and Veterans (SM/V). This condition merits special attention in SM/V, particularly in the aftermath of deployments. Military deployments frequently give rise to posttraumatic stress disorder (PTSD) and deployment-related mild TBI traumatic brain injury (TBI), potentially leading to manifestations of behavioral dyscontrol. Examine associations among PTSD symptom severity, deployment-related mild traumatic brain injury, and behavioral dyscontrol among SM/V. Secondary cross-sectional data analysis from the Long-Term Impact of Military-Relevant Brain Injury Consortium - Chronic Effects of Neurotrauma Consortium prospective longitudinal study among SM/V (  = 1,808). Univariable and multivariable linear regression models assessed the association and interaction effects between PTSD symptom severity, as assessed by the PTSD Checklist for the Diagnostic and Statistical Manual, 5th edition (PCL-5), and deployment-related mild TBI on behavioral dyscontrol, adjusting for demographics, pain, social support, resilience, and general self-efficacy. Among the 1,808 individuals in our sample, PTSD symptom severity (  = 0.23, 95% CI: 0.22, 0.25,