The impact of the Xpert MTB/RIF screening among hospitalized patients with pneumonia on timely isolation of patients with pulmonary tuberculosis

In South Korea where the tuberculosis (TB) burden is intermediate, the risk of in-hospital transmission of TB remains high. We conducted a retrospective cohort study of 244 inpatients diagnosed with pulmonary TB (2015–2018) to evaluate the impact of the Xpert MTB/RIF assay (Xpert) screening on timel...

Full description

Saved in:
Bibliographic Details
Published in:Scientific reports 2021-01, Vol.11 (1), p.1694-1694, Article 1694
Main Authors: Han, Seung Beom, Park, Joonhong, Ji, Seul Ki, Jang, So Hee, Shin, Soyoung, Kim, Myung Sook, Kim, Seung Soo, Park, Sun Hee
Format: Article
Language:English
Subjects:
692/699/255/1856
692/700/1538
Disease transmission
Humanities and Social Sciences
Microscopy
multidisciplinary
Polymerase chain reaction
Regression analysis
Science
Science (multidisciplinary)
Tuberculosis
Citations: Items that this one cites
Items that cite this one
Online Access:Get full text
Tags: Add Tag
No Tags, Be the first to tag this record!
Description
Summary:In South Korea where the tuberculosis (TB) burden is intermediate, the risk of in-hospital transmission of TB remains high. We conducted a retrospective cohort study of 244 inpatients diagnosed with pulmonary TB (2015–2018) to evaluate the impact of the Xpert MTB/RIF assay (Xpert) screening on timely isolation. TB screening was performed with smear microscopy and a polymerase chain reaction test, and the Xpert was additionally used from November 2016. Among all patients with pulmonary TB, the median time-to-isolation was significantly reduced (22.6 vs. 69.7 h; p  
ISSN:2045-2322
2045-2322
DOI:10.1038/s41598-020-79639-7