Association between age-related kidney function and vascular subclinical state in a healthy Chinese population

Imbalances between CYSC and CTSB are connected with atherosclerosis (AS), coronary heart disease, and chronic kidney disease with aging-related phenotypes. In this study, we analyzed the association between renal function, measured by CYSC and estimated glomerular filtration rate (eGFR), and vascula...

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Bibliographic Details
Published in:Chinese medical journal 2021-10, Vol.134 (19), p.2376-2378
Main Authors: Wang, Nan, Bai, Xiao-Juan, Han, Lu-Lu, Han, Wen, Sun, Xue-Feng, Chen, Xiang-Mei
Format: Article
Language:English
Subjects:
Age
Aging
Asians
Blood pressure
Body mass index
Cardiovascular disease
Carotid arteries
China - epidemiology
Cholesterol
Chronic illnesses
Correspondence
Creatinine
Diabetes
Fasting
Flow velocity
Glomerular Filtration Rate
Humans
Hypertension
Kidney
Kidney diseases
Laboratories
Lipoproteins
Males
Regression analysis
Risk Factors
Uric acid
Variance analysis
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Summary:Imbalances between CYSC and CTSB are connected with atherosclerosis (AS), coronary heart disease, and chronic kidney disease with aging-related phenotypes. In this study, we analyzed the association between renal function, measured by CYSC and estimated glomerular filtration rate (eGFR), and vascular parameters in a healthy Chinese population. Blood samples were collected at least 10 h after overnight fasting, and blood biochemistry samples, including serum creatinine (SCr), uric acid (UA), fasting blood glucose (FBG), serum triglycerides (TG), total cholesterol (TC), high-density lipoprotein cholesterol (HDL-C), and low-density lipoprotein cholesterol (LDL-C), were tested with standard assays. Age, body mass index (BMI), systolic blood pressure (SBP), FBG, SCr, CYSC, UA, TC, LDL, IMT, D, IMT/D, PI, and RI gradually decreased with the progression from low to high eGFR value (P 
ISSN:0366-6999
2542-5641
DOI:10.1097/CM9.0000000000001422