Assessment Of Endometrial Integrin Beta 5 In Women With Unexplained Recurrent Pregnancy Loss

To examine the relationship between endometrial integrin beta 5 level and risk of recurrent pregnancy loss. The descriptive, prospective, observational, case-controlstudy was conducted at the Kafrelsheikh University Hospital, Egypt, from January to May 2022, and comprised women aged up to 35 years w...

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Bibliographic Details
Published in:Journal of the Pakistan Medical Association 2023-04, Vol.73(Suppl 4) (4), p.S114-S117
Main Authors: Fathy, Ahmed Mohamed, Rizk, Ahmed Youssef, El Azeez Nosair, Nahla Abd, Abdelkarim, Ahmed Mohamed, Ellakany, Mostafa Farag
Format: Article
Language:English
Subjects:
Abortion
Abortion, Habitual
Adult
Endometrium
Female
Gynaecology
Habitual
Humans
Infertility, Female
Integrins
Obstetrics
Pathology
Pregnancy
Prospective Studies
Young Adult
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Summary:To examine the relationship between endometrial integrin beta 5 level and risk of recurrent pregnancy loss. The descriptive, prospective, observational, case-controlstudy was conducted at the Kafrelsheikh University Hospital, Egypt, from January to May 2022, and comprised women aged up to 35 years with at least 1 live birth delivery beyond 20-week gestation with normal thyroid and prolactin levels. Age-matched normal fertile women were enrolled as controls. All the participants were subjected to detailed history and complete clinical examination. Endometrial integrin beta 5 was assessed using an antibody sandwich enzyme-linked immunosorbent assay. Data was analysed using SPSS 20. Of the 50 subjects, 25(50%) were cases with a mean age of 26.72±2.64 years, and 25(50%) were controls with a mean age of 25.36±2.16 years. The integrin beta 5 level was significantly lower among the cases than the controls (p
ISSN:0030-9982
DOI:10.47391/JPMA.EGY-S4-24