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Vector competence of Anopheles and Culex mosquitoes for Zika virus

Zika virus is a newly emergent mosquito-borne flavivirus that has caused recent large outbreaks in the new world, leading to dramatic increases in serious disease pathology including Guillain-Barre syndrome, newborn microcephaly, and infant brain damage. Although mosquitoes are thought to be the pri...

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Bibliographic Details
Published in:PeerJ (San Francisco, CA) CA), 2017-03, Vol.5, p.e3096-e3096, Article e3096
Main Authors: Dodson, Brittany L, Rasgon, Jason L
Format: Article
Language:English
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Summary:Zika virus is a newly emergent mosquito-borne flavivirus that has caused recent large outbreaks in the new world, leading to dramatic increases in serious disease pathology including Guillain-Barre syndrome, newborn microcephaly, and infant brain damage. Although mosquitoes are thought to be the primary mosquito species driving infection, the virus has been isolated from dozens of mosquito species, including and species, and we lack a thorough understanding of which mosquito species to target for vector control. We exposed , , and mosquitoes to blood meals supplemented with two Zika virus strains. Mosquito bodies, legs, and saliva were collected five, seven, and 14 days post blood meal and tested for infectious virus by plaque assay. Regardless of titer, virus strain, or timepoint, , , and mosquitoes were refractory to Zika virus infection. We conclude that , , and mosquitoes likely do not contribute significantly to Zika virus transmission to humans. However, future studies should continue to explore the potential for other novel potential vectors to transmit the virus.
ISSN:2167-8359
2167-8359
DOI:10.7717/peerj.3096