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Clostridium perfringens -Opportunistic Foodborne Pathogen, Its Diversity and Epidemiological Significance
The species is associated with various environments, such as soils, sewage, and food. However, it is also a component of the gastrointestinal (GI) microflora (i.e., microbiota) of sick and healthy humans and animals. is linked with different systemic and enteric diseases in livestock and humans, suc...
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| Published in: | Pathogens (Basel) 2023-05, Vol.12 (6), p.768 |
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| Main Authors: | , , , , , |
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| container_title | Pathogens (Basel) |
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| creator | Grenda, Tomasz Jarosz, Aleksandra Sapała, Magdalena Grenda, Anna Patyra, Ewelina Kwiatek, Krzysztof |
| description | The
species is associated with various environments, such as soils, sewage, and food. However, it is also a component of the gastrointestinal (GI) microflora (i.e., microbiota) of sick and healthy humans and animals.
is linked with different systemic and enteric diseases in livestock and humans, such as gas gangrene, food poisoning, non-foodborne diarrhoea, and enterocolitis. The strains of this opportunistic pathogen are known to secrete over 20 identified toxins that are considered its principal virulence factors.
belongs to the anaerobic bacteria community but can also survive in the presence of oxygen. The short time between generations, the multi-production capability of toxins and heat-resistant spores, the location of many virulence genes on mobile genetic elements, and the inhabitance of this opportunistic pathogen in different ecological niches make
a very important microorganism for public health protection. The epidemiological evidence for the association of these strains with
-meditated food poisoning and some cases of non-foodborne diseases is very clear and well-documented. However, the genetic diversity and physiology of
should still be studied in order to confirm the importance of suspected novel virulence traits. A very significant problem is the growing antibiotic resistance of
strains. The aim of this review is to show the current basic information about the toxins, epidemiology, and genetic and molecular diversity of this opportunistic pathogen. |
| doi_str_mv | 10.3390/pathogens12060768 |
| format | article |
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species is associated with various environments, such as soils, sewage, and food. However, it is also a component of the gastrointestinal (GI) microflora (i.e., microbiota) of sick and healthy humans and animals.
is linked with different systemic and enteric diseases in livestock and humans, such as gas gangrene, food poisoning, non-foodborne diarrhoea, and enterocolitis. The strains of this opportunistic pathogen are known to secrete over 20 identified toxins that are considered its principal virulence factors.
belongs to the anaerobic bacteria community but can also survive in the presence of oxygen. The short time between generations, the multi-production capability of toxins and heat-resistant spores, the location of many virulence genes on mobile genetic elements, and the inhabitance of this opportunistic pathogen in different ecological niches make
a very important microorganism for public health protection. The epidemiological evidence for the association of these strains with
-meditated food poisoning and some cases of non-foodborne diseases is very clear and well-documented. However, the genetic diversity and physiology of
should still be studied in order to confirm the importance of suspected novel virulence traits. A very significant problem is the growing antibiotic resistance of
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species is associated with various environments, such as soils, sewage, and food. However, it is also a component of the gastrointestinal (GI) microflora (i.e., microbiota) of sick and healthy humans and animals.
is linked with different systemic and enteric diseases in livestock and humans, such as gas gangrene, food poisoning, non-foodborne diarrhoea, and enterocolitis. The strains of this opportunistic pathogen are known to secrete over 20 identified toxins that are considered its principal virulence factors.
belongs to the anaerobic bacteria community but can also survive in the presence of oxygen. The short time between generations, the multi-production capability of toxins and heat-resistant spores, the location of many virulence genes on mobile genetic elements, and the inhabitance of this opportunistic pathogen in different ecological niches make
a very important microorganism for public health protection. The epidemiological evidence for the association of these strains with
-meditated food poisoning and some cases of non-foodborne diseases is very clear and well-documented. However, the genetic diversity and physiology of
should still be studied in order to confirm the importance of suspected novel virulence traits. A very significant problem is the growing antibiotic resistance of
strains. The aim of this review is to show the current basic information about the toxins, epidemiology, and genetic and molecular diversity of this opportunistic pathogen.</description><subject>anaerobe</subject><subject>Anaerobic bacteria</subject><subject>Animal diseases</subject><subject>Antibiotic resistance</subject><subject>Autopsies</subject><subject>Clostridium</subject><subject>Clostridium perfringens</subject><subject>Diarrhea</subject><subject>Ecological niches</subject><subject>Enterocolitis</subject><subject>Epidemiology</subject><subject>Experiments</subject><subject>Food</subject><subject>Food contamination</subject><subject>Food poisoning</subject><subject>Foodborne diseases</subject><subject>Foodborne pathogens</subject><subject>Gangrene</subject><subject>Gas gangrene</subject><subject>Genetic diversity</subject><subject>infection</subject><subject>Lactose</subject><subject>Livestock</subject><subject>Medical research</subject><subject>Microflora</subject><subject>Microorganisms</subject><subject>Opportunist infection</subject><subject>Pathogens</subject><subject>Poisoning</subject><subject>Public health</subject><subject>Review</subject><subject>Sewage</subject><subject>Spores</subject><subject>Strains (organisms)</subject><subject>toxinotype</subject><subject>Toxins</subject><subject>Tuberculosis</subject><subject>Virulence</subject><subject>Virulence factors</subject><issn>2076-0817</issn><issn>2076-0817</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2023</creationdate><recordtype>article</recordtype><sourceid>PIMPY</sourceid><sourceid>DOA</sourceid><recordid>eNplkk1v1DAQhiMEolXpD-CCInHhQGD8kdg5IbRtYaVKRQLOlmNPUq8SO9hJpf57vOxSteDLjD3vPPZrTVG8JvCBsRY-znq5DQP6RCg0IBr5rDilOVYgiXj-KD8pzlPaQV4S9vuXxQkTTNS8lqeF24whLdFZt07ljLGPzu-hZXUzzyEuq3dpcaa8CsF2IXosvx3vfV9ul1ReuDuMyS33pfa2vJydxcmFMQzO6LH87gbv-px6g6-KF70eE54f41nx8-ryx-ZrdX3zZbv5fF0Z3vKlIpIxCYxygr3gKKwWaKVoakIkpQBNr22uosSWWNTAuDYNN5LUDRBOKDsrtgeuDXqn5ugmHe9V0E79OQhxUDpmSyMqaqCrWy7B8I5r0ndtC7qxQmLPG21MZn06sOa1m9Aa9EvU4xPo04p3t2oId4oAA15DmwnvjoQYfq2YFjW5ZHActcewJkUlg6YRLa2z9O0_0l1Yo89_lVW0lZxn_1lFDioTQ0oR-4fXEFD7wVD_DUbuefPYxkPH3zFgvwGm8bcj</recordid><startdate>20230526</startdate><enddate>20230526</enddate><creator>Grenda, Tomasz</creator><creator>Jarosz, Aleksandra</creator><creator>Sapała, Magdalena</creator><creator>Grenda, Anna</creator><creator>Patyra, Ewelina</creator><creator>Kwiatek, Krzysztof</creator><general>MDPI AG</general><general>MDPI</general><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>7T7</scope><scope>8FD</scope><scope>8FE</scope><scope>8FH</scope><scope>ABUWG</scope><scope>AFKRA</scope><scope>AZQEC</scope><scope>BBNVY</scope><scope>BENPR</scope><scope>BHPHI</scope><scope>C1K</scope><scope>CCPQU</scope><scope>DWQXO</scope><scope>FR3</scope><scope>GNUQQ</scope><scope>HCIFZ</scope><scope>LK8</scope><scope>M7P</scope><scope>P64</scope><scope>PIMPY</scope><scope>PQEST</scope><scope>PQQKQ</scope><scope>PQUKI</scope><scope>7X8</scope><scope>5PM</scope><scope>DOA</scope><orcidid>https://orcid.org/0000-0003-4619-128X</orcidid><orcidid>https://orcid.org/0000-0002-3827-2314</orcidid><orcidid>https://orcid.org/0000-0001-5808-2051</orcidid></search><sort><creationdate>20230526</creationdate><title>Clostridium perfringens -Opportunistic Foodborne Pathogen, Its Diversity and Epidemiological Significance</title><author>Grenda, Tomasz ; 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species is associated with various environments, such as soils, sewage, and food. However, it is also a component of the gastrointestinal (GI) microflora (i.e., microbiota) of sick and healthy humans and animals.
is linked with different systemic and enteric diseases in livestock and humans, such as gas gangrene, food poisoning, non-foodborne diarrhoea, and enterocolitis. The strains of this opportunistic pathogen are known to secrete over 20 identified toxins that are considered its principal virulence factors.
belongs to the anaerobic bacteria community but can also survive in the presence of oxygen. The short time between generations, the multi-production capability of toxins and heat-resistant spores, the location of many virulence genes on mobile genetic elements, and the inhabitance of this opportunistic pathogen in different ecological niches make
a very important microorganism for public health protection. The epidemiological evidence for the association of these strains with
-meditated food poisoning and some cases of non-foodborne diseases is very clear and well-documented. However, the genetic diversity and physiology of
should still be studied in order to confirm the importance of suspected novel virulence traits. A very significant problem is the growing antibiotic resistance of
strains. The aim of this review is to show the current basic information about the toxins, epidemiology, and genetic and molecular diversity of this opportunistic pathogen.</abstract><cop>Switzerland</cop><pub>MDPI AG</pub><pmid>37375458</pmid><doi>10.3390/pathogens12060768</doi><orcidid>https://orcid.org/0000-0003-4619-128X</orcidid><orcidid>https://orcid.org/0000-0002-3827-2314</orcidid><orcidid>https://orcid.org/0000-0001-5808-2051</orcidid><oa>free_for_read</oa></addata></record> |
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| subjects | anaerobe Anaerobic bacteria Animal diseases Antibiotic resistance Autopsies Clostridium Clostridium perfringens Diarrhea Ecological niches Enterocolitis Epidemiology Experiments Food Food contamination Food poisoning Foodborne diseases Foodborne pathogens Gangrene Gas gangrene Genetic diversity infection Lactose Livestock Medical research Microflora Microorganisms Opportunist infection Pathogens Poisoning Public health Review Sewage Spores Strains (organisms) toxinotype Toxins Tuberculosis Virulence Virulence factors |
| title | Clostridium perfringens -Opportunistic Foodborne Pathogen, Its Diversity and Epidemiological Significance |
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