Estimation of Salivary Parameters among Autoimmune Thyroiditis Patients

• Published in: Journal of clinical and diagnostic research 2017-07, Vol.11 (7), p.ZC01-ZC04
• Main Authors: Syed, Yasmeen Amthul, Reddy, Bh Satheesh, Ramamurthy, T K, Rajendra, Kavitha, Nerella, Narendra Kumar, Krishnan, Meenakshi, Ramesh, M V, Mohammed, Rezwana Begum
• Format: Article
• Language: English
• Subjects: autoimmune thyroidits; buffer capacity; Dentistry Section; hyposalivation; unstimulated salivary flow rate
• ISSN: 2249-782X; 0973-709X
• DOI: 10.7860/JCDR/2017/26444.10128

Saliva is a complex secretion that protects and lubricates the oral cavity. Various systemic diseases and their treatment alter the salivary gland function; one such disease is Autoimmune Thyroid Disease (AITD). AITD has been postulated to exert its hormonal influence on the salivary glands, leading to reduced salivary output. There's a paucity of literature, verifying the stated conjunction in human subjects. The aim was to investigate the salivary profile in AITD patients and its comparison with controls. Descriptive cross-sectional comparative study was conducted using convenience sampling method for screening the presence of thyroid disorders. Two groups comprising of 30 patients in each group diagnosed with autoimmune hypothyroiditis (n=30) and hyperthyroiditis (n=30) respectively and thirty healthy volunteers who were age and sex matched were included as controls. Saliva was collected and evaluated for Unstimulated Salivary Flow Rate (USSFR), pH and buffer capacity. ANOVA and Tukey post-hoc test was performed to find the statistical significance and for pairwise comparison. Statistically significant difference was observed between autoimmune hypothyroiditis, autoimmune hyperthyroiditis and control group with respect to USSFR (p