Epidemiological features of spinal intradural tumors, a single-center clinical study in Beijing, China

• Published in: BMC musculoskeletal disorders 2024-08, Vol.25 (1), p.613-7, Article 613
• Main Authors: Liu, Longqi, Shi, Liang, Su, Yibing, Wang, Keda, Wang, Hanbin
• Format: Article
• Language: English
• Subjects: Adolescent; Adult; Aged; Aged, 80 and over; Beijing - epidemiology; Brain cancer; Cancer; Cancer therapies; Central nervous system diseases; Cervical Vertebrae - pathology; Cervical Vertebrae - surgery; Chairs; Cysts; Ependymoma - epidemiology; Ependymoma - pathology; Ependymoma - surgery; Epidemiology; Female; Females; Glioma; Hospitals; Humans; Male; Males; Meningeal Neoplasms - epidemiology; Meningeal Neoplasms - pathology; Meningeal Neoplasms - surgery; Meningioma; Meningioma - epidemiology; Meningioma - pathology; Meningioma - surgery; Metastases; Metastasis; Middle Aged; Nervous system; Neurilemmoma - epidemiology; Neurilemmoma - pathology; Neurilemmoma - surgery; Patients; Retrospective Studies; Retrospective study; Schwann cells; Socioeconomic factors; Socioeconomic status; Spinal cord; Spinal cord diseases; Spinal cord neoplasms; Spinal Cord Neoplasms - epidemiology; Spinal Cord Neoplasms - surgery; Spondylosis; Surgery; Thoracic Vertebrae - pathology; Thoracic Vertebrae - surgery; Thorax; Tumors; Vertebrae; Young Adult
• ISSN: 1471-2474; 1471-2474
• DOI: 10.1186/s12891-024-07741-2

Spinal intradural tumors are rare and heterogeneous in histological type, aggressiveness, and symptomatology, and there is a lack of data about them. This study investigated the epidemiological features of spinal intradural tumors. This retrospective analysis included patients with spinal intradural tumors who underwent surgical treatment at the Myelopathy and Spondylosis Ward Beijing Jishuitan Hospital between January 2012 and December 2022. This study included 1321 patients [aged 47.19 ± 14.90 years, 603 (45.65%) males] with spinal intradural tumors. The most common histological subtype was schwannoma [n = 511 (38.68%)], followed by spinal meningioma [n = 184 (13.93%)] and ependymoma [n = 101 (7.65%)]. Fifteen (1.14%) patients were diagnosed with metastatic spinal intradural tumors as a presentation of another primary cancer type. The spinal intradural tumors were mostly found in the lumbar region [n = 436 (33.01%)], followed by the thoracic vertebrae [n = 390 (29.52%)], cervical vertebrae [n = 154 (11.66%)], and thoracolumbar region [n = 111 (8.40%)]. Schwannomas mostly affected the lumbar region [n = 256 (52.64%)], spinal meningiomas in the thoracic region [n = 153 (83.15)], and ependymomas in the lumbar region [56 (55.45%)]. The de novo metastases were mostly found in the lumbar region [n = 8 (53.33%)]. According to the results of our single-center study, the most common spinal intradural tumor in Northern China is schwannoma, followed by spinal meningioma and ependymoma.