U-Shaped Relation of Dietary Thiamine Intake and New-Onset Hypertension

• Published in: Nutrients 2022-08, Vol.14 (16), p.3251
• Main Authors: Zhang, Yuanyuan, Zhang, Yanjun, Yang, Sisi, Ye, Ziliang, Wu, Qimeng, Liu, Mengyi, Zhou, Chun, He, Panpan, Jiang, Jianping, Liang, Min, Wang, Guobao, Hou, Fanfan, Liu, Chengzhang, Qin, Xianhui
• Format: Article
• Language: English
• Subjects: Adult; Age; Alcohol; Analysis; Antihypertensives; Blood pressure; Blood Pressure - physiology; Body mass index; Cohort analysis; Diet; Diet - adverse effects; Diet therapy; Dietary intake; dietary thiamine intake; Education; Food; Health aspects; Health surveys; Humans; Hypertension; Hypertension - epidemiology; Hypertension - etiology; nationwide cohort study; new-onset hypertension; Nutrients; Nutrition; Nutrition Surveys; Potassium; Prevention; Pyrimidines; Risk factors; Surveys; Thiamine; Variance analysis; Vitamin B; Vitamin B1; Womens health
• ISSN: 2072-6643; 2072-6643
• DOI: 10.3390/nu14163251

Background: To examine the relation of dietary thiamine intake with risk of new-onset hypertension in the general adults. Methods: A total of 12,177 participants without hypertension at baseline from China Health and Nutrition Survey (CHNS) were included. The study outcome was new-onset hypertension, which was defined as a systolic blood pressure ≥140 mm Hg or a diastolic blood pressure ≥90 mm Hg or under antihypertensive treatment or diagnosed by physician during the follow-up. Results: A total of 4269 participants occurred new-onset hypertension over a median follow-up of 6.1 years. Overall, there was a U-shaped relation (p for nonlinearity